15753-62-5

Basic information

• Product Name: <2-(4-Methoxy-anilino)-vinyl>-phenyl-keton
• Synonyms: <2-(4-Methoxy-anilino)-vinyl>-phenyl-keton
• CAS NO: 15753-62-5
• Molecular Weight: 253.301
• Mol File: 15753-62-5.mol

Chemical Properties

• CAS DataBase Reference: <2-(4-Methoxy-anilino)-vinyl>-phenyl-keton(CAS DataBase Reference)
• NIST Chemistry Reference: <2-(4-Methoxy-anilino)-vinyl>-phenyl-keton(15753-62-5)
• EPA Substance Registry System: <2-(4-Methoxy-anilino)-vinyl>-phenyl-keton(15753-62-5)

Safety Data

• Hazardous Substances Data: 15753-62-5(Hazardous Substances Data)

Upstream product

• 98-86-2 acetophenone 
• 1201-93-0 1-phenyl-3-dimethylaminoprop-2-enone 
• 104-94-9 4-methoxy-aniline 
• 10349-38-9 p-methoxyphenylisonitrile 
• 72374-65-3 (E)-[1-phenylpropylidene]-(4-methoxyphenyl)amine 
• 20265-97-8 p-anisidine hydrochloride 
• 15397-33-8 3-Oxo-3-phenylpropanal 
• 72374-74-4 N-1-(2,2-Dichlor-1-phenyl-propyliden)-p-methoxy-anilin 

Downstream Products

• 1434474-99-3 (1-(4-methoxyphenyl)-6-methyl-4,6-diphenyl-1,6-dihydropyridin-3-yl)(phenyl)methanone 
• 1242517-24-3 (2E,4E)-2,4-bis(((4-methoxyphenyl)amino)methylene)-1,5-diphenylpentane-1,5-dion 
• 126933-59-3 (1-(4-methoxyphenyl)-1H-1,2,3-triazol-4-yl)(phenyl)methanone 
• 1418126-76-7 methyl 5-benzoyl-1-(4-methoxyphenyl)-2-oxo-1,2-dihydropyridine-4-carboxylate 

Relevant articles and documents

Organocatalytic activation of isocyanides: N-heterocyclic carbene-catalyzed enaminone synthesis from ketones

The first example of the use of an N-heterocyclic carbene (NHC) as an organocatalyst for the activation of isocyanides was demonstrated. On the basis of previous reports on the interaction between NHCs and isocyanides, we developed a catalytic cycle invol

Base-Promoted Synthesis of N-Substituted 1,2,3-Triazoles via Enaminone-Azide Cycloaddition Involving Regitz Diazo Transfer

The domino reactions between NH-based secondary enaminones and tosyl azide have been developed for the synthesis of various N-substituted 1,2,3-triazoles by employing t-BuONa as the base promoter. Through a key Regitz diazo-transfer process with tosyl azi

Novel tetrahydropyrimidine-adamantane hybrids as anti-inflammatory agents: Synthesis, structure and biological evaluation

A series of novel (3-((3s,5s,7s)-adamantan-1-yl)-1-alkyl/aralkyl/aryl-1,2,3,4-tetrahydroyrimidin-5-yl)(aryl)methanones (5a-j) has been synthesized by the reaction of 1-aryl-3-(alkyl/aralkyl/aryl)aminoprop-2-en-1-ones 3a-j, 1-adamantanamine 4 and formaldehyde under thermal conditions. The structures of the products (5a-j) have been established with the help of spectral and analytical data. The stereochemistry of the products was established by X-ray crystallographic studies of a representative product (3-((3s,5s,7s)-adamantan-1-yl)-1-methyl-1,2,3,4-tetrahydropyrimidin-5-yl)(4-chlorophenyl) methanone (5g) of the series. The target adamantane-tetrahydropyrimidine hybrids 5a-j were evaluated for their anti-inflammatory activities as a result of which compounds 5e (R=C6H5CH2, Ar=C6H5), 5i (R=CH3, Ar=4-CH3C6H4), 5j (R=C6H5CH2, Ar=4-CH3C6H4) and 5g (R=CH3, Ar=4-ClC6H4) were found to exhibit excellent and promising anti-inflammatory activities.