157555-32-3Relevant academic research and scientific papers
Design and synthesis of seco-oxysterol analogs as potential inhibitors of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase gene transcription
Larsen,Spilman,Yagi,Dinh,Hart,Hess
, p. 2343 - 2351 (2007/10/02)
The synthesis and biological activity of a series of seco-oxysterol analogs designed to be inhibitors of transcription of the gene for 3- hydroxy-3-methylglutaryl-Coenzyme A reductase (HMGR) are described. The compound possessing the most significant acti
