157560-07-1Relevant academic research and scientific papers
Chemoselective conversion of conjugated nitroalkenes into ketones by sodium borohydride-hydrogen peroxide: A new synthesis of 4-oxoalkanoic acids, dihydrojasmone and (±)exo-brevicomin
Ballini,Bosica
, p. 723 - 726 (1994)
A new, simple, cheap, and practical procedure for the direct transformation of α,β-unsaturated nitroalkenes into ketones has been realized by the NaBH4/H2O2 system. By this method, other functional groups such as C-C double bonds, ketals or aromatic nitro groups were preserved. Application of this methodology to the preparation of 4-oxoalkanoic acids, dihydrojasmone, and (±)-exobrevicomin is also reported.
A Novel, Two-step, Mild and Simple Synthesis of β-, γ-, and δ-Oxo Esters from ω-Nitro Esters.
Ballini, Roberto,Bosica, Giovanna
, p. 2901 - 2912 (2007/10/02)
A convenient, mild, and simple synthesis of β-, γ-, and δ-oxo esters was achieved from ω-nitro esters.A solvent-free nitroaldol reaction of the ω-nitro esters 2 with the aldehydes 1 on alumina, followed by in situ dehydration, with addition of dichloromethane and warming gave the conjugated nitroalkenes 3, which can be converted into the carbonyl derivatives 4 by sodium hypophosphite.
