157560-07-1

Basic information

• Product Name: (E)-methyl 4-nitro-7-phenyl-4-heptenoate
• Synonyms: (E)-methyl 4-nitro-7-phenyl-4-heptenoate
• CAS NO: 157560-07-1
• Molecular Weight: 263.293
• Mol File: 157560-07-1.mol

Chemical Properties

• CAS DataBase Reference: (E)-methyl 4-nitro-7-phenyl-4-heptenoate(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-methyl 4-nitro-7-phenyl-4-heptenoate(157560-07-1)
• EPA Substance Registry System: (E)-methyl 4-nitro-7-phenyl-4-heptenoate(157560-07-1)

Safety Data

• Hazardous Substances Data: 157560-07-1(Hazardous Substances Data)

Upstream product

• 104-53-0 3-phenyl-propionaldehyde 
• 13013-02-0 methyl 4-nitrobutyrate 

Downstream Products

• 53668-52-3 4-oxo-7-phenylheptanoic acid 
• 160723-52-4 methyl 4-oxo-7-phenylheptanoate 

Relevant articles and documents

Chemoselective conversion of conjugated nitroalkenes into ketones by sodium borohydride-hydrogen peroxide: A new synthesis of 4-oxoalkanoic acids, dihydrojasmone and (±)exo-brevicomin

A new, simple, cheap, and practical procedure for the direct transformation of α,β-unsaturated nitroalkenes into ketones has been realized by the NaBH4/H2O2 system. By this method, other functional groups such as C-C double bonds, ketals or aromatic nitro groups were preserved. Application of this methodology to the preparation of 4-oxoalkanoic acids, dihydrojasmone, and (±)-exobrevicomin is also reported.

A Novel, Two-step, Mild and Simple Synthesis of β-, γ-, and δ-Oxo Esters from ω-Nitro Esters.

A convenient, mild, and simple synthesis of β-, γ-, and δ-oxo esters was achieved from ω-nitro esters.A solvent-free nitroaldol reaction of the ω-nitro esters 2 with the aldehydes 1 on alumina, followed by in situ dehydration, with addition of dichloromethane and warming gave the conjugated nitroalkenes 3, which can be converted into the carbonyl derivatives 4 by sodium hypophosphite.