157567-63-0

Basic information

• Product Name: L-Leucine, N-methyl-, (1R)-2-oxo-2-(phenylmethoxy)-1-(phenylmethyl)ethyl ester
• CAS NO: 157567-63-0
• Molecular Formula: C23H29NO4
• Molecular Weight: 383.488
• Mol File: 157567-63-0.mol

Chemical Properties

• CAS DataBase Reference: L-Leucine, N-methyl-, (1R)-2-oxo-2-(phenylmethoxy)-1-(phenylmethyl)ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Leucine, N-methyl-, (1R)-2-oxo-2-(phenylmethoxy)-1-(phenylmethyl)ethyl ester(157567-63-0)
• EPA Substance Registry System: L-Leucine, N-methyl-, (1R)-2-oxo-2-(phenylmethoxy)-1-(phenylmethyl)ethyl ester(157567-63-0)

Safety Data

• Hazardous Substances Data: 157567-63-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Research and Development:
L-Leucine, N-methyl, (1R)-2-oxo-2-(phenylmethoxy)-1-(phenylmethyl)ethyl ester serves as a valuable building block for the synthesis of peptides and proteins. Its unique structure allows it to be a key component in the design and creation of novel bioactive molecules, potentially leading to the development of new drugs and therapies.
Used in Peptide and Protein Synthesis:
In the field of biochemistry, L-Leucine, N-methyl-, (1R)-2-oxo-2-(phenylmethoxy)-1-(phenylmethyl)ethyl ester is utilized for its potential to enhance the synthesis of peptides and proteins. Its incorporation into these biological macromolecules can impart new properties or functions, which is crucial for understanding their mechanisms and for developing new therapeutic agents.
Used in Drug Development:
Due to its distinctive molecular structure, L-Leucine, N-methyl, (1R)-2-oxo-2-(phenylmethoxy)-1-(phenylmethyl)ethyl ester may have applications in the development of innovative drugs. Its ability to be integrated into complex molecular frameworks makes it a candidate for targeted drug design, potentially leading to more effective treatments with fewer side effects.

Upstream product

• 13139-15-6 N-tert-butoxycarbonyl-L-leucine 
• 20312-36-1 L-3-phenyllactic acid 
• 53363-89-6 N-t-butoxycarbonyl-N-methyl-L-leucine 
• 7622-21-1 benzyl-(S)-(-)-2-hydroxy-3-phenylpropionate 
• 100-39-0 benzyl bromide 

Downstream Products

• 157567-64-1 benzyl N-Boc-N-methyl-L-leucyl-D-lactyl-N-methyl-L-leucyl-3-phenyl-D-lactate 
• 188908-40-9 (S)-2-(tert-Butoxycarbonyl-methyl-amino)-4-methyl-pentanoic acid (R)-1-{[(S)-1-((R)-1-{[(S)-1-((R)-1-benzyloxycarbonyl-2-phenyl-ethoxycarbonyl)-3-methyl-butyl]-methyl-carbamoyl}-ethoxycarbonyl)-3-methyl-butyl]-methyl-carbamoyl}-2-phenyl-ethyl ester 
• 188908-24-9 (S)-Pyrrolidine-1,2-dicarboxylic acid 2-((R)-1-{[(S)-1-((R)-1-benzyloxycarbonyl-2-phenyl-ethoxycarbonyl)-3-methyl-butyl]-methyl-carbamoyl}-ethyl) ester 1-tert-butyl ester 
• 188908-25-0 N-Boc-L-prolyl-D-lactyl-N-methyl-L-leucyl-3-phenyl-D-lactic acid 
• 188908-41-0 N-Boc-N-methyl-L-leucyl-3-phenyl-D-lactyl-N-methyl-L-leucyl-D-lactyl-N-methyl-L-leucyl-3-phenyl-D-lactic acid 
• 188908-28-3 L-prolyl-D-lactyl-N-methyl-L-leucyl-3-phenyl-D-lactyl-N-methyl-L-leucyl-D-lactyl-N-methyl-L-leucyl-3-phenyl-D-lactic acid 
• 187851-87-2 N-methyl-L-leucyl-3-phenyl-D-lactyl-N-methyl-L-leucyl-D-lactyl-N-methyl-L-leucyl-3-phenyl-D-lactyl-L-pipecolyl-D-lactic acid 
• 546141-57-5 N-methyl-L-leucyl-3-phenyl-D-lactyl-N-methyl-L-leucyl-D-lactyl-N-methyl-L-leucyl-3-phenyl-D-lactyl-L-azepanyl-D-lactic acid 
• 188908-27-2 pyrrolidine-2-carboxylic acid 1-{[1-(1-{[1-(1-{[1-(1-benzyloxycarbonyl-2-phenyl-ethoxycarbonyl)-3-methyl-butyl]-methyl-carbamoyl}-ethoxycarbonyl)-3-methyl-butyl]-methyl-carbamoyl}-2-phenyl-ethoxycarbonyl)-3-methyl-butyl]-methyl-carbamoyl}-ethyl ester 
• 188908-43-2 1-[2-(4-methyl-2-{methyl-[2-(4-methyl-2-{methyl-[2-(4-methyl-2-methylamino-pentanoyloxy)-3-phenyl-propionyl]-amino}-pentanoyloxy)-propionyl]-amino}-pentanoyloxy)-3-phenyl-propionyl]-piperidine-2-carboxylic acid 1-benzyloxycarbonyl-ethyl ester 
• 546141-59-7 1-[2-(4-methyl-2-{methyl-[2-(4-methyl-2-{methyl-[2-(4-methyl-2-methylamino-pentanoyloxy)-3-phenyl-propionyl]-amino}-pentanoyloxy)-propionyl]-amino}-pentanoyloxy)-3-phenyl-propionyl]-azepane-2-carboxylic acid 1-benzyloxycarbonyl-ethyl ester 
• 188908-26-1 C₆₂H₈₆N₄O₁₅ 
• 188908-42-1 C₆₃H₈₈N₄O₁₅ 
• 546141-58-6 C₆₄H₉₀N₄O₁₅ 

Relevant articles and documents

Total Synthesis of the Anthelmintic Cyclodepsipeptide, PF1022A

The anthelmintic cyclooctadepsipeptide PF1022A and its antipode were synthesized starting from L-Nα-Boc-leucine (for PF1022A), D-N4a-Boc-leucine (for the antipode), L-lactic acid, and L-phenyllactic acid using Mitsunobu reaction and/