1575766-74-3Relevant academic research and scientific papers
Efficient synthesis of some new 2,3-dimethylquinoxaline-1-oxides using bis(acetoxy)phenyl-λ 3-iodane as an oxidant
Aggarwal, Ranjana,Rani, Chinu,Sumran, Garima
, p. 923 - 928 (2014)
A series of 2-(arylimino)-3-(hydroxyimino)butanes 3a-g, easily accessed by the condensation of variously substituted anilines 1a-g with biacetyl monoxime 2, were efficiently cyclized to afford 2,3-dimethylquinoxaline-1-oxides 4a-g using bis(acetoxy)phenyl-λ 3-iodane as an oxidant. This methodology utilizes a commercially available and environmental benign oxidant to achieve the title compounds in excellent yields under mild conditions. [Supplementary materials are available for this article. Go to the publisher's online edition of Synthetic Communications for the following free supplemental resource(s): Full experimental and spectral details.]
