157590-59-5

Basic information

• Product Name: 2-CHLORO-4,5-DIAMINOBENZOTRIFLUORIDE
• Synonyms: 2-CHLORO-4,5-DIAMINOBENZOTRIFLUORIDE;4-CHLORO-5-TRIFLUOROMETHYL-BENZENE-1,2-DIAMINE;2-Amino-4-chloro-5-(trifluoromethyl)phenylamine;2-AMino-4-chloro-5-(trifluoroMethyl)aniline;3,4-Diamino-6-chlorobenzotrifluoride;5-Chloro-4-(trifluoromethyl)benzene-1,2-diamine;4-Chloro-5-trifluoroMethyl-o-phenylenediaMine, 95%;4-Chloro-5-(trifluoromethyl)benzene-1,2-diamine 97%
• CAS NO: 157590-59-5
• Molecular Formula: C₇H₆ClF₃N₂
• Molecular Weight: 210.58
• Mol File: 157590-59-5.mol
• Article Data: 7

Chemical Properties

• Melting Point: 61-63°
• Boiling Point: 305.1 °C at 760 mmHg
• Flash Point: 138.3 °C
• Appearance: White to brown/Solid
• Density: 1.510
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• Water Solubility: Slightly soluble in water.
• CAS DataBase Reference: 2-CHLORO-4,5-DIAMINOBENZOTRIFLUORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-4,5-DIAMINOBENZOTRIFLUORIDE(157590-59-5)
• EPA Substance Registry System: 2-CHLORO-4,5-DIAMINOBENZOTRIFLUORIDE(157590-59-5)

Safety Data

• Hazard Codes: Xi
• HazardClass: IRRITANT
• Hazardous Substances Data: 157590-59-5(Hazardous Substances Data)

Usage

Uses

4-Chloro-5-trifluoromethyl-o-phenylenediamine has application in dietary supplements, pharmaceutical or cosmeticeuticals.

Upstream product

• 167415-22-7 5-Amino-2-chloro-4-nitrobenzotrifluoride 
• 1026318-97-7 N-(5-Chloro-2-nitro-4-trifluoromethyl-phenyl)-acetamide 
• 546434-30-4 acetic acid-(3-chloro-4-trifluoromethyl-anilide) 
• 445-13-6 3-chloro-4-(trifluoromethyl)aniline 
• 35375-74-7 5-chloro-2-nitro-4-(trifluoromethyl)aniline 

Downstream Products

• 1078728-28-5 C₂₁H₁₈ClF₃N₂O₃ 

Relevant articles and documents

ANTIBIOTIC COMPOUNDS

The present invention relates to antibiotic compounds of formula (I), to compositions containing these compounds and to methods of treating bacterial diseases and infections using the compounds. The compounds find application in the treatment of infection with, and diseases caused by, Gram-positive and/or Gram-negative bacteria, and in particular in the treatment of infection with, and diseases caused by, Neisseria gonorrhoeae.

HETEROCYCLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE

The present invention relates to compounds and methods which may be useful as inhibitors of H1R and/or H4R for the treatment or prevention of inflammatory, autoimmune, allergic, and ocular diseases.

BENZIMIDAZOLE DERIVATIVES AND THEIR USE AS VANILLOID RECEPTOR LIGANDS

Compounds of formula (I) are useful in the treatment of vanilloid-receptor-meditated diseases, such as inflammatory or neuropathic pain and diseases involving sensory nerve function such as asthma, rheumatoid arthritis, osteoarthritis, inflammatory bowel disorders, urinary incontinence, migraine and psoriasis.