445-13-6

Usage

Uses

3-Chloro-4-trifluoromethylaniline

InChI:InChI=1/C7H5ClF3N/c8-6-3-4(12)1-2-5(6)7(9,10)11/h1-3H,12H2

Upstream product

• 7587-89-5 N-(3-chloro-4-trifluoromethyl-phenyl)-phthalimide 
• 75-63-8 Bromotrifluoromethane 
• 108-42-9 3-chloro-aniline 
• 151504-80-2 3-Chloro-4-trifluoromethyl-nitrobenzene 
• 41252-96-4 3-chloro-4-iodonitrobenzene 
• 100-34-5 benzene diazonium chloride 

Downstream Products

• 546434-30-4 acetic acid-(3-chloro-4-trifluoromethyl-anilide) 
• 68105-69-1 (3-Chloro-4-trifluoromethyl-phenyl)-(2,4-dinitro-naphthalen-1-yl)-amine 
• 72773-12-7 (3-Chloro-4-trifluoromethyl-phenyl)-(4-nitro-2,6-bis-trifluoromethyl-phenyl)-amine 
• 39886-32-3 5-methyl-oxazolidine-3-carboxylic acid (3-chloro-4-trifluoromethyl-phenylcarbamoyl)-amide 
• 23794-99-2 1,3-Bis-(3-chloro-4-trifluoromethyl-phenyl)-urea 
• 929910-69-0 3-methyl-5-nitro-3H-imidazole-4-carboxylic acid (3-chloro-4-trifluoromethyl-phenyl)-amide 
• 873576-69-3 3-(3-chloro-4-trifluoromethylphenylselanyl)-1H-[1,2,4]triazole 
• 35375-74-7 5-chloro-2-nitro-4-(trifluoromethyl)aniline 
• 157590-59-5 4-chloro-5-(trifluoromethyl)-1,2-diaminobenzene 
• 1026318-97-7 N-(5-Chloro-2-nitro-4-trifluoromethyl-phenyl)-acetamide 
• 32333-53-2 4-chloro-3-trifluoromethylbenzenesulfonyl chloride 
• 894801-69-5 phenyl [3-chloro-4-(trifluoromethyl)phenyl]carbamate 
• 894801-68-4 2,2,2-trichloro-N-[3-chloro-4-(trifluoromethyl)phenyl]acetamide 

Relevant academic research and scientific papers

Thiourea inhibitors of herpes viruses. Part 1: Bis-(aryl)thiourea inhibitors of CMV

Bis-(aryl)thioureas were found to be potent and selective inhibitors of cytomegalovirus (CMV) in cultured HFF cells. Of these, the thiazole analogue 38 was investigated as a potential development candidate.

Reactions of Trifluoromethyl Bromide and Related Halides: Part 10. Perfluoroalkylation of Aromatic Compounds induced by Sulphur Dioxide Radical Anion Precursors

Perfluoroalkylation of electron-rich aromatic compounds with trifluoromethyl bromide, or long-chain perfluoroalkyl iodides, was performed in the presence of sodium dithionite or zinc-sulphur dioxide.This alkylation occurred at the ortho and para positions relative to the amino or hydroxy substitutent.Pyrroles were perfluoroalkylated regioselectively at the 2-position.This alkylation was interpreted as a radical aromatic substitution; the formation of the perfluoroalkyl radical can be induced by a single-electron transfer from sulphur dioxide radical anion to the perfluoroalkyl halide.

Combating fungi with dicarboxylic acid mono-arylhydrazides

Combating fungi with dicarboxylic acid mono-aryl-hydrazides of the formula STR1 in which R1 and R2 each independently is hydrogen, halogen, C1 -C4 alkyl, C1 -C4 alkoxy, C1 -C4 alkylmercapto, trihalogenomethyl, trihalogenomethoxy, trihalogenomethylmercapto or nitro, X is an alkylene, alkenylene, cycloalkylene, cycloalkenylene, cycloalkadienylene or phenylene radical, and M is hydrogen or one equivalent of a metal, or a salt thereof.

Experimental and quantum chemical study on nano-copper immobilized on magnetic graphitic carbon nitride core shell particles; a reusable heterogeneous catalyst toward reduction of nitro arenes

A new magnetic material, which named CuFe2O4?SiO2?g-C3N4/Cu with a core/shell morphology has been designed and synthesized. For the first time ever, the mixture of carbon and g-C3N4 layer was applied as an effective linker for immobilization of Cu metal on the catalyst. The physiochemical properties of the catalyst were identified by XRD, FT-IR, VSM, FE-SEM and TEM characterization techniques. The reduction of nitro compounds to the corresponding amines was investigated in the presence of NaBH4 at 55 °C in water. Quantum chemical study reveals that the addition of Cu atoms to the g-C3N4 layer induce a slight structural deformation via changing the bond lengths and bond orders, also the type of interaction of Cu atoms and nitrogen atoms of g-C3N4 is mainly electrostatic in nature. Induced pattern of charge distribution provided by Electrostatic Potential Map exhibits the attractive regions for electrophiles and nucleophiles interacting with this system.