157609-76-2

Upstream product

• 30004-67-2 N,S-dimethyl-S-phenylsulfoximine 
• 10458-14-7 (2R,5S)-menthone 
• 80482-67-3 (-)-(R)-N,S-dimethyl-S-phenylsulfoximine 
• 157609-88-6 C₁₈H₂₉NO₂S 

Downstream Products

• 33993-53-2 N,S-dimethyl-S-phenylsulfoximine 
• 80482-67-3 (-)-(R)-N,S-dimethyl-S-phenylsulfoximine 
• 38618-25-6 (1S,2S,5R)-1,5-dimethyl-2-(1-methylethyl)cyclohexan-1-ol 
• 157609-88-6 C₁₈H₂₉NO₂S 
• 92207-96-0 C₁₅H₁₉NO₂S 
• 92207-91-5 C₁₈H₂₉NO₂S 
• 92207-92-6 C₁₇H₂₇NO₂S 
• 92207-98-2 C₁₉H₂₃NO₂S 
• 92207-90-4 C₂₀H₂₅NO₂S 
• 92208-00-9 C₂₃H₂₅NO₃S 
• 38618-25-6 (1R,2S,5R)-1,5-dimethyl-2-(1-methylethyl)cyclohexan-1-ol 
• 92207-95-9 C₁₅H₁₉NO₂S 
• 73808-92-1 C₁₈H₂₉NO₂S 
• 73808-92-1 C₁₈H₂₉NO₂S 

Relevant academic research and scientific papers

(N-Methylphenylsulfoximidoyl)methyllithium: A versatile reagent for the determination of absolute configuration of six-membered ring ketones

The diastereotopic chemical shift differences of the 1H and 13C NMR signals of the adducts formed by addition of (N-methylphenylsulfoximidoyl)methyllithium (2) to cyclic ketones has been studied. The stereodifferentiation of the proton and carbon atoms follow a very regular pattern annd the rule that can be drawn provides an alternative and complementary method to earlier procedures for the determinations of absolute configuration of six-membered ring ketones.

N,S-DIMETHYL-S-PHENYLSULFOXIMINE. A REAGENT FOR THE OPTICAL RESOLUTION OF KETONES

The addition of the α-lithio derivative of (+)- or (-)-N,S-dimethyl-S-phenylsulfoximine to selected dl-ketones was carried out at -78 deg C in tetrahydrofuran followed by acid quench at that temperature to produce mixtures of diastereomeric β-hydroxysulfoximines.The optically-active diastereomers were chromatographically separated on silica gel.The purified diastereomers were thermolyzed at ca. 130 deg to produce optically-active ketones and the optically-active sulfoximine which could be recycled.