157635-92-2Relevant academic research and scientific papers
Enzymatic preparation of homochiral 2-(N-carbobenzyloxypiperid-4-yl)-1,3-propanediol monoacetate. A facile entry to both enantiomers of 3-hydroxymethylquinuclidine
Guanti,Banfi,Brusco,Narisano
, p. 537 - 540 (2007/10/02)
Both enantiomers of monoacetate 1 have been prepared in high ee by lipase catalyzed monohydrolysis of the prochiral diacetate 3 and by monoacetylation of the corresponding diol 4.3-Hydroxymethylquinuclidine 2 was then synthesized in both enantiomeric form
