157639-66-2

Upstream product

• 157639-65-1 (2S,3R,4E)-3-tert-butyldimethylsilyloxy-1-<2,3:4,6-di-O-isopropylidene-5a-carba-β-D-xylo-hex-5(5a)-enopyranosylamino>-2-(2,4-dinitrophenyl)amino-4-octadecene 
• 162019-91-2 (2S,3R,4E)-3-(tert-butyldimethylsilyloxy)-1,2-(2,4-dinitrophenyl)imino-4-octadecene 
• 157639-70-8 (2S,3R,4E)-3-(tert-butyldimethylsilyloxy)-2-(2,4-dinitrophenyl)amino-4-octadecen-1-ol 
• 157639-71-9 (2S,3R,4E)-3-(tert-butyldimethylsilyloxy)-2-(2,4-dinitrophenyl)amino-1-iodo-4-octadecene 
• 70-34-8 2,4-Dinitrofluorobenzene 
• 114299-64-8 (2S,3S,4E)-2-azido-3-O-(tert-butyldimethylsilyl)-4-octadecen-1,3-diol 
• 103348-49-8 2-azido-sphingosine 
• 132016-22-9 (1S,2R,9S,10S)-9-amino-4,4,12,12-tetramethyl-3,5,11,13-tetraoxatricyclo[8.3.0.0^2,7]tridec-7-ene 

Relevant academic research and scientific papers

Synthesis of Glycosylceramide Analogs Composed of Imino-Linked Unsaturated 5a-Carbaglycosyl Residues: Potent and Specific Gluco- and Galactocerebrosidase Inhibitors

5a-Carba-β-glucosyl- E-3 and galactosylceramide analogs E-4 were synthesized by coupling of the protected derivatives 5 of β-valienamine and 15 of 4-epi-β-valienamine with the aziridines E-6 and Z-6, as the sphingosine precursors, respectively, and subseq

Synthesis of glucosylceramide analogues. Imino-linked 5a-carbaglycosylceramides, potent and specific glucocerebrosidase inhibitors

Imino-linked carbocyclic analogues (E)- and (Z)-2 of glucosylceramide 1 have been synthesized and shown to be potent and specific inhibitors against glucocerebrosidase.