157665-29-7

Upstream product

• 85803-25-4 di-tert-butyl N-(2-fluoro-4-nitrobenzoyl)-l-glutamate 
• 85803-27-6 di-tert-butyl N-(4-amino-2-fluorobenzoyl)-L-glutamate 
• 403-23-6 2-fluoro-4-nitrobenzoyl chloride 
• 403-24-7 2-fluoro-4-nitrobenzoic acid 
• 157665-26-4 di-tert-butyl <2-fluoro-4-benzoyl>-L-glutamate 
• 124-63-0 methanesulfonyl chloride 

Relevant academic research and scientific papers

Novel prodrugs of alkylating agents derived from 2-fluoro- and 3- fluorobenzoic acids for antibody-directed enzyme prodrug therapy

The synthesis of six novel fluorinated potential prodrugs for antibody- directed enzyme prodrug therapy is described. The [2- and 3-fluoro-4-[bis(2- chloroethyl)amino]benzoyl]-L-glutamic acid (9 and 21), their bis(mesyloxy)ethyl derivatives (7 and 19), an