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TERT-BUTYL 3-FLUORO-4-NITROBENZOATE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 157665-52-6 Structure
  • Basic information

    1. Product Name: TERT-BUTYL 3-FLUORO-4-NITROBENZOATE
    2. Synonyms: TERT-BUTYL 3-FLUORO-4-NITROBENZOATE
    3. CAS NO:157665-52-6
    4. Molecular Formula: C11H12FNO4
    5. Molecular Weight: 241.2156832
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 157665-52-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 337.9±32.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.250±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: TERT-BUTYL 3-FLUORO-4-NITROBENZOATE(CAS DataBase Reference)
    10. NIST Chemistry Reference: TERT-BUTYL 3-FLUORO-4-NITROBENZOATE(157665-52-6)
    11. EPA Substance Registry System: TERT-BUTYL 3-FLUORO-4-NITROBENZOATE(157665-52-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 157665-52-6(Hazardous Substances Data)

157665-52-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 157665-52-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,7,6,6 and 5 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 157665-52:
(8*1)+(7*5)+(6*7)+(5*6)+(4*6)+(3*5)+(2*5)+(1*2)=166
166 % 10 = 6
So 157665-52-6 is a valid CAS Registry Number.

157665-52-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl 3-fluoro-4-nitrobenzoate

1.2 Other means of identification

Product number -
Other names Benzoic acid,3-fluoro-4-nitro-,1,1-dimethylethyl ester

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:157665-52-6 SDS

157665-52-6Relevant articles and documents

STAT INHIBITORY COMPOUNDS AND COMPOSITIONS

-

Paragraph 0269, (2021/09/11)

Provided herein are compounds and pharmaceutical compositions comprising said compounds that are useful for the inhibition of Signal Transducer and Activator of Transcription 5a and 5b (STAT5). Furthermore, the subject compounds and compositions are usefu

COMPOUNDS, COMPOSITIONS, AND METHODS FOR MODULATING FERROPTOSIS AND TREATING EXCITOTOXIC DISORDERS

-

Paragraph 0164; 0180, (2020/06/19)

The present disclosure provides, inter alia, a compound having the structure (1). Also provided are compositions containing a pharmaceutically acceptable carrier and one or more compounds according to the present disclosure. Further provided are methods f

GLP-1 Agonists and Uses Thereof

-

Paragraph 0436, (2018/07/05)

Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, 7-aza- and 4,7-diaza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.

Allosteric Inhibitors, Crystallography, and Comparative Analysis Reveal Network of Coordinated Movement across Human Herpesvirus Proteases

Acker, Timothy M.,Gable, Jonathan E.,Bohn, Markus-Frederik,Jaishankar, Priyadarshini,Thompson, Michael C.,Fraser, James S.,Renslo, Adam R.,Craik, Charles S.

supporting information, p. 11650 - 11653 (2017/09/07)

Targeting of cryptic binding sites represents an attractive but underexplored approach to modulating protein function with small molecules. Using the dimeric protease (Pr) from Kaposi's sarcoma-associated herpesvirus (KSHV) as a model system, we sought to dissect a putative allosteric network linking a cryptic site at the dimerization interface to enzyme function. Five cryogenic X-ray structures were solved of the monomeric protease with allosteric inhibitors bound to the dimer interface site. Distinct coordinated movements captured by the allosteric inhibitors were also revealed as alternative states in room-temperature X-ray data and comparative analyses of other dimeric herpesvirus proteases. A two-step mechanism was elucidated through detailed kinetic analyses and suggests an enzyme isomerization model of inhibition. Finally, a representative allosteric inhibitor from this class was shown to be efficacious in a cellular model of viral infectivity. These studies reveal a coordinated dynamic network of atomic communication linking cryptic binding site occupancy and allosteric inactivation of KHSV Pr that can be exploited to target other members of this clinically relevant family of enzymes.

NOVEL PYRROLOY2,3-d¨PYRIMIDINE COMPOUND

-

Page/Page column 63, (2011/12/12)

Disclosed is a novel pyrrolo[2,3-d]pyrimidine compound represented by formula [I] or a pharmacologically acceptable salt thereof, which has a GPR119 receptor agonistic activity and is useful for a pharmaceutical. In formula [I], E represents a group repre

BENZIMIDAZOLECARBOXAMIDES AS INHIBITORS OF FAK

-

Page/Page column 107, (2010/11/17)

This invention relates to benzimadolecarboxamides of formula (I) which are inhibitors of focal adhesion kinase, and as such are useful for treating proliferative diseases

BENZIMIDAZOLONE CHYMASE INHIBITORS

-

Page/Page column 189, (2009/01/20)

Disclosed are small molecule inhibitors which are useful in treating various diseases and conditions involving chymase.

4-Acetylamino-3-(imidazol-1-yl)-benzoic acids as novel inhibitors of influenza sialidase

Howes, Peter D.,Cleasby, Anne,Evans, Derek N.,Feilden, Helen,Smith, Paul W.,Sollis, Steven L.,Taylor, Neil,Wonacott, Alan J.

, p. 225 - 234 (2007/10/03)

Two methods for the synthesis of 4-acetylamino benzoic acids substituted at the 3-position with imidazoles are described. Many of the compounds are inhibitors of influenza virus sialidases with levels of activity similar to the recently described 4-acetylamino-3-guanidino-benzoic acid (BANA 113).

Novel prodrugs of alkylating agents derived from 2-fluoro- and 3- fluorobenzoic acids for antibody-directed enzyme prodrug therapy

Springer,Niculescu-Duvaz,Pedley

, p. 2361 - 2370 (2007/10/02)

The synthesis of six novel fluorinated potential prodrugs for antibody- directed enzyme prodrug therapy is described. The [2- and 3-fluoro-4-[bis(2- chloroethyl)amino]benzoyl]-L-glutamic acid (9 and 21), their bis(mesyloxy)ethyl derivatives (7 and 19), an

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