157683-48-2

Upstream product

• 157683-46-0 3-Benzoylsulfanyl-5-tert-butoxycarbonylamino-pentanoic acid ethyl ester 
• 69619-21-2 5-tert-butoxycarbonylamino-3-oxo-pentanoic acid ethyl ester 
• 69619-24-5 ethyl 5-tert-butoxycarbonylamino-3-hydroxyvalerate 
• 157683-47-1 5-tert-Butoxycarbonylamino-3-(4-methoxy-benzylsulfanyl)-pentanoic acid ethyl ester 

Downstream Products

• 108308-80-1 (5R,6S)-6-((R)-1-Hydroxy-ethyl)-7-oxo-3-(5,6,7,8-tetrahydro-imidazo[1,2-a]pyridin-7-ylsulfanyl)-4-thia-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 108309-09-7 7-(4-Methoxy-benzylsulfanyl)-5,6,7,8-tetrahydro-imidazo[1,2-a]pyridine 
• 157683-49-3 6-Ethoxy-4-(4-methoxy-benzylsulfanyl)-2,3,4,5-tetrahydro-pyridine 

Relevant academic research and scientific papers

Synthesis and antibacterial activity of new 2-substituted penems. II

A series of new penems (4 ~ 17), having a bicyclic imidazole moiety as the C-2 substituent, has been synthesized. The antimicrobial activity of these compounds and their susceptibility to renal dehydropeptidase-1 (DHP-1) are elucidated, and their structure-activity relationships are discussed.