1577222-14-0 Usage
Description
Diroximel fumarate is a prodrug form of monomethyl fumarate . It undergoes esterase cleavage in the gut to release monomethyl fumarate. Formulations containing diroximel fumarate have been used in the treatment of relapsing-remitting multiple sclerosis.
Uses
Diroximel Fumarate is a novel oral fumarate in development for the treatment of patients with relapsing forms of multiple sclerosis.
Check Digit Verification of cas no
The CAS Registry Mumber 1577222-14-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,7,7,2,2 and 2 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1577222-14:
(9*1)+(8*5)+(7*7)+(6*7)+(5*2)+(4*2)+(3*2)+(2*1)+(1*4)=170
170 % 10 = 0
So 1577222-14-0 is a valid CAS Registry Number.
1577222-14-0Relevant articles and documents
METHOD FOR PRODUCING MONOMETHYL FUMARATE COMPOUNDS
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Page/Page column 53, (2017/07/14)
The present invention relates to a novel method for preparing monomethyl fumarate, which can preferably be used in the treatment and/or prevention of systemic diseases, autoimmune diseases, inflammatory diseases such as multiple sclerosis and psoriasis. Further, the present invention relates to the use of specific compounds as intermediates in the process for preparing a monomethyl fumarate prodrug.
