1577232-55-3Relevant academic research and scientific papers
Hydrohalogenative aromatization of multiynes promoted by ruthenium alkylidene complexes
Karmakar, Rajdip,Wang, Kung-Pern,Yun, Sang Young,Mamidipalli, Phani,Lee, Daesung
, p. 4782 - 4788 (2016)
A new functionalization method of arynes promoted by a novel catalytic role of the Grubbs-type ruthenium alkylidene complex is described. Through a sequence of aryne formation followed by their halo-functionalization, various bis-1,3-diynes were directly converted to functionalized aryl chlorides, bromides and iodides in good yields in the presence of a catalytic amount of a ruthenium alkylidene complex and halogenated hydrocarbons such as CH2Cl2, CHCl3, CH2Br2, and CH2I2. The utility of this novel transformation is demonstrated by a formal synthesis of herbindole B.
Convenient one-step construction of yne-functionalized aryl halides through domino cyclization from tetraynes
Zhang, Hao,Hu, Qiong,Li, Lidong,Hu, Yimin,Zhou, Pingping,Zhang, Xiaorong,Xie, Haifeng,Yin, Fei,Hu, Yadong,Wang, Shaowu
supporting information, p. 3335 - 3337 (2014/03/21)
An efficient method for the construction of fused yne-substituted aryl halides by reaction of unactivated linear tetraynes with allyl halides via domino C-C coupling and formation of C-X bonds in the presence of Pd(OAc) 2/PPh3 was de
