157751-99-0

Basic information

• Product Name: 2'-(3-benzyloxy-24-norcholan-23-yl)-2'-4',4'-trimethyl-4',5'-dihydrooxazoline-N-oxyl
• Synonyms: 2'-(3-benzyloxy-24-norcholan-23-yl)-2'-4',4'-trimethyl-4',5'-dihydrooxazoline-N-oxyl
• CAS NO: 157751-99-0
• Molecular Formula: C36H56 N O3
• Molecular Weight: 0
• Mol File: 157751-99-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2'-(3-benzyloxy-24-norcholan-23-yl)-2'-4',4'-trimethyl-4',5'-dihydrooxazoline-N-oxyl(CAS DataBase Reference)
• NIST Chemistry Reference: 2'-(3-benzyloxy-24-norcholan-23-yl)-2'-4',4'-trimethyl-4',5'-dihydrooxazoline-N-oxyl(157751-99-0)
• EPA Substance Registry System: 2'-(3-benzyloxy-24-norcholan-23-yl)-2'-4',4'-trimethyl-4',5'-dihydrooxazoline-N-oxyl(157751-99-0)

Safety Data

• Hazardous Substances Data: 157751-99-0(Hazardous Substances Data)

Upstream product

• 917-64-6 methyl magnesium iodide 
• 134878-47-0 2'-(3α-Benzyloxy-24-norcholan-23-yl)-4',4'-dimethyl-4',5'-dihydrooxazole 
• 100-39-0 benzyl bromide 

Relevant articles and documents

SYNTHESIS OF 2'-(3α-BENZYLOXY-24-NORCHOLAN-23-YL)-2',4',4'-TRIMETHYL-4',5'-DIHYDROOXAZOLINE-N-OXYL - A NEW POTENTIAL SPIN PROBE FOR BIOMEMBRANES

The synthesis of a new steroidal nitroxide, viz. 2'-(3α-benzyloxy-24-norcholan-23-yl)-2',4',4'-trimethyl-4',5'-dihydrooxazoline-N-oxyl 7, a potential spin probe for biomembranes is described.The title compound in improved yield could be obtained by a direct Grignard reaction on the oxaziridine 4.This effected a one-step reduction in the overall synthetic sequence.The methodology of the Grignard reaction on the oxaziridine to yield the nitroxide is reported for the first time.In dilute solutions, the isotropic ESR parameters for 7 have been measured.