15776-99-5Relevant academic research and scientific papers
Selective C-H trifluoromethylation of benzimidazoles through photoredox catalysis
Gao, Guo-Lin,Yang, Chao,Xia, Wujiong
, p. 1041 - 1044 (2017)
The protocol presented here is a new strategy for visible light induced C-H trifluoromethylation at C4 of benzimidazoles using Togni's reagent in the presence of fac-Ir(ppy)3. Its advantages are its operational simplicity, mild reaction conditions, low catalyst loading and wide substrate scope in which electron-withdrawing, electron-donating groups and different protecting groups are tolerated.
Resorcinarene-mono-benzimidazolium salts as NHC ligands for Suzuki-Miyaura cross-couplings catalysts
I?ci, ümit,Aygün, Muhittin,Sevincek, Resul,Zorlu, Yunus,Dumoulin, Fabienne
, p. 1300 - 1309 (2015)
Two mono-benzimidazolium salts of resorcinarene have been prepared and used as ligands in Suzuki-Miyaura cross-coupling reactions. They have been fully characterized by 1H and 13C NMR, MALDI, and FT-IR spectroscopic methods, and their structures were confirmed by X-ray diffraction analysis. These two new resorcinarene-based mono-benzimidazolium salts showed good catalytic activity for coupling reactions in DMF. The highest conversion was achieved for arylation of 4-bromotoluene using the resorcinarenyl mono-dimethylbenzimidazolium salt.
Cu-Catalyzed Regioselective C-H Alkylation of Benzimidazoles with Aromatic Alkenes
He, Yu-Ting,Mao, Yang-Jie,Hao, Hong-Yan,Xu, Zhen-Yuan,Lou, Shao-Jie,Xu, Dan-Qian
supporting information, p. 8250 - 8255 (2020/11/18)
Herein we report a novel Cu-catalyzed regioselective C2-H alkylation of benzimidazoles with aromatic alkenes. The reaction features exclusive regioselectivity and broad substrate scope in the intermolecular alkylation of benzimidazoles with terminal and i
Intramolecular arylation of benzimidazoles via Pd(II)/Cu(I) catalyzed cross-dehydrogenative coupling
Pereira, Kyle C.,Porter, Ashley L.,Deboef, Brenton
supporting information, p. 1729 - 1732 (2014/03/21)
Electron poor benzimidazole substrates were arylated via an intramolecular cross-dehydrogenative coupling (CDC) reaction. These CDC reactions were catalyzed by a Pd(II)/Cu(I) catalyst system, capable of producing moderate yields on a large library of substrates. The substrate scope consisted of tethered arene-benzimidazoles that upon coupling, produced a fused polycyclic motif.
