1577989-89-9

Upstream product

• 1577989-85-5 (R)-6-bromo-4-(2-hydroxyethyl)-1-(4-methoxybenzyl)-4-(trifluoromethyl)-3,4-dihydroquinazolin-2(1H)-one 
• 1360590-84-6 C₁₇H₁₂BrF₃N₂O₂ 
• 1577989-36-6 (R)-phenyl-2-(6-bromo-1-(4-methoxybenzyl)-2-oxo-4-(trifluoromethyl)-1,2,3,4-tetrahydroquinazolin-4-yl)acetate 

Relevant academic research and scientific papers

Highly enantioselective decarboxylative Mannich reaction of malonic acid half oxyesters with cyclic trifluoromethyl ketimines: Synthesis of β-amino esters and anti-HIV drug DPC 083

An organocatalytic enantioselective decarboxylative Mannich reaction of malonic acid half oxyesters with cyclic ketimines was developed for the preparation of enantioenriched β-amino esters with a quaternary stereogenic center and the anti-HIV drug DPC 083 (see scheme). Copyright