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1578154-74-1

(3S)-4-[[(4S)-4-(4-chloro-3-fluoro-phenyl)-5-methoxycarbonyl-2-thiazol-2-yl-1,4-dihydropyrimidin-6-yl]methyl]morpholine-3-carboxylic acid is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • (3S)-4-[[(4S)-4-(4-chloro-3-fluoro-phenyl)-5-methoxycarbonyl-2-thiazol-2-yl-1,4-dihydropyrimidin-6-yl]methyl]morpholine-3-carboxylic acid

    Cas No: 1578154-74-1

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  • 1578154-74-1 Structure

  • Basic information

    1. Product Name: (3S)-4-[[(4S)-4-(4-chloro-3-fluoro-phenyl)-5-methoxycarbonyl-2-thiazol-2-yl-1,4-dihydropyrimidin-6-yl]methyl]morpholine-3-carboxylic acid
    2. Synonyms: (3S)-4-[[(4S)-4-(4-chloro-3-fluoro-phenyl)-5-methoxycarbonyl-2-thiazol-2-yl-1,4-dihydropyrimidin-6-yl]methyl]morpholine-3-carboxylic acid
    3. CAS NO:1578154-74-1
    4. Molecular Formula:
    5. Molecular Weight: 494.931
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1578154-74-1.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: (3S)-4-[[(4S)-4-(4-chloro-3-fluoro-phenyl)-5-methoxycarbonyl-2-thiazol-2-yl-1,4-dihydropyrimidin-6-yl]methyl]morpholine-3-carboxylic acid(CAS DataBase Reference)
    10. NIST Chemistry Reference: (3S)-4-[[(4S)-4-(4-chloro-3-fluoro-phenyl)-5-methoxycarbonyl-2-thiazol-2-yl-1,4-dihydropyrimidin-6-yl]methyl]morpholine-3-carboxylic acid(1578154-74-1)
    11. EPA Substance Registry System: (3S)-4-[[(4S)-4-(4-chloro-3-fluoro-phenyl)-5-methoxycarbonyl-2-thiazol-2-yl-1,4-dihydropyrimidin-6-yl]methyl]morpholine-3-carboxylic acid(1578154-74-1)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1578154-74-1(Hazardous Substances Data)

1578154-74-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1578154-74-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,7,8,1,5 and 4 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1578154-74:
(9*1)+(8*5)+(7*7)+(6*8)+(5*1)+(4*5)+(3*4)+(2*7)+(1*4)=201
201 % 10 = 1
So 1578154-74-1 is a valid CAS Registry Number.

1578154-74-1Downstream Products

1578154-74-1Relevant articles and documents

A New Approach of Mitigating CYP3A4 Induction Led to the Discovery of Potent Hepatitis B Virus (HBV) Capsid Inhibitor with Optimal ADMET Profiles

Lin, Xianfeng,Shi, Houguang,Zhang, Weixing,Qiu, Zongxing,Zhou, Zheng,Dey, Fabian,Zhong, Sheng,Qiu, Hongxia,Xie, Jianxun,Zhou, Xue,Yang, Guang,Tang, Guozhi,Shen, Hong C.,Zhu, Wei

, p. 10352 - 10361 (2019/11/29)

Described herein is a new approach to mitigate CYP3A4 induction. In this unconventional approach, a fine-tuning of the dihedral angle between the C4 phenyl and the dihydropyrimidine core of the heteroaryldihydropyrimidine (HAP) class of capsid inhibitors

PROCESS FOR THE PREPARATION OF 4-PHENYL-5-ALKOXYCARBONYL-2-THIAZOL-2-YL-1,4-DIHYDROPYRIMIDINE ANALOGUES

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Page/Page column 13; 14; 15; 16; 19; 20, (2016/07/27)

The present invention relates to a process for synthesizing a compound of formula (I), (I), wherein R1 is phenyl, which is unsubstituted, or once, twice or three times substituted by halogen; R2 is C1-6/su

Novel 6-amino acid heteroaryldihydropyrimidines for the treatment and prophylaxis of hepatitis B virus infection

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Paragraph 0215; 0320; 0424, (2015/02/19)

The invention provides novel compounds having the general formula: wherein R1, R2, R3, R4 and A are as described herein, compositions including the compounds and methods of using the compounds.

6-AMINO ACID HETEROARYLDIHYDROPYRIMIDINES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION

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Page/Page column 95; 121; 122, (2014/03/26)

The invention provides novel compounds having the general formula:, wherein R1, R2, R3, R4 and A are as described herein, compositions including the compounds and methods of using the compounds.

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