157826-18-1

Basic information

• Product Name: {(3aR,4R,6R,6aR)-6-[6-Amino-2-((S)-1-methyl-2-phenyl-ethylamino)-purin-9-yl]-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl}-methanol
• CAS NO: 157826-18-1
• Molecular Weight: 440.502
• Mol File: 157826-18-1.mol

Chemical Properties

• CAS DataBase Reference: {(3aR,4R,6R,6aR)-6-[6-Amino-2-((S)-1-methyl-2-phenyl-ethylamino)-purin-9-yl]-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl}-methanol(CAS DataBase Reference)
• NIST Chemistry Reference: {(3aR,4R,6R,6aR)-6-[6-Amino-2-((S)-1-methyl-2-phenyl-ethylamino)-purin-9-yl]-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl}-methanol(157826-18-1)
• EPA Substance Registry System: {(3aR,4R,6R,6aR)-6-[6-Amino-2-((S)-1-methyl-2-phenyl-ethylamino)-purin-9-yl]-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl}-methanol(157826-18-1)

Safety Data

• Hazardous Substances Data: 157826-18-1(Hazardous Substances Data)

Upstream product

• 146-77-0 2-Chloroadenosine 
• 24639-06-3 ((3aR,4R,6R,6aR)-6-(6-amino-2-chloro-9H-purin-9-yl)-2,2-dimethyltetrahydrofuro[3,4-d][1,3]dioxol-4-yl)methanol 
• 51-64-9 dexamfetamine 

Relevant articles and documents

The synthesis and biological activity of a highly selective adenosine A(2a) receptor agonist

Three novel nucleosides 1, 2, and 3 were prepared that contained side chains at the 2-position of adenosine. Compound 1 was shown to be the most selective A(2a) receptor agonist reported to date having an A1/A2 ratio of 2400. In addition, compound 1 was shown to reduce blood pressure in rats and dogs with only minimal effects on heart rate.