157887-88-2

Basic information

• Product Name: {3-[[3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-propoxy]-(2,2,5,7,8-pentamethyl-chroman-6-sulfonyl)-amino]-propyl}-carbamic acid 1-biphenyl-4-yl-1-methyl-ethyl ester
• Synonyms: {3-[[3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-propoxy]-(2,2,5,7,8-pentamethyl-chroman-6-sulfonyl)-amino]-propyl}-carbamic acid 1-biphenyl-4-yl-1-methyl-ethyl ester
• CAS NO: 157887-88-2
• Molecular Weight: 781.97
• Mol File: 157887-88-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {3-[[3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-propoxy]-(2,2,5,7,8-pentamethyl-chroman-6-sulfonyl)-amino]-propyl}-carbamic acid 1-biphenyl-4-yl-1-methyl-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: {3-[[3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-propoxy]-(2,2,5,7,8-pentamethyl-chroman-6-sulfonyl)-amino]-propyl}-carbamic acid 1-biphenyl-4-yl-1-methyl-ethyl ester(157887-88-2)
• EPA Substance Registry System: {3-[[3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yl)-propoxy]-(2,2,5,7,8-pentamethyl-chroman-6-sulfonyl)-amino]-propyl}-carbamic acid 1-biphenyl-4-yl-1-methyl-ethyl ester(157887-88-2)

Safety Data

• Hazardous Substances Data: 157887-88-2(Hazardous Substances Data)

Upstream product

• 157887-83-7 [3-(1,3-Dioxo-1,3-dihydro-isoindol-2-yloxy)-propyl]-carbamic acid 9H-fluoren-9-ylmethyl ester 
• 157887-84-8 N-(aminooxypropyl)phthalimide 
• 112160-39-1 2,2,5,7,8-pentamethylchroman-6-sulfonyl chloride 
• 31140-37-1 methyl 4-[({[2-(biphenyl-4-yl)propan-2-yl]oxy}carbonyl)oxy]benzoate 
• 209115-31-1 3-[1-(Biphenyl-4-yl)-1-methylethoxycarbonylamino]propanol 
• 157887-87-1 2,2,5,7,8-Pentamethyl-chroman-6-sulfonic acid [3-(1,3-dioxo-1,3-dihydro-isoindol-2-yl)-propoxy]-amide 

Relevant articles and documents

The Synthesis of Oxa-Analogues and Homologues of Naturally Occuring Polyamines

A number of polyamine oxa-analogues 14a-d, 19 have been synthesized.Spermidine oxa-analogues and homologues 14 were made from N-(aminooxypropyl)phthalimide 8a which was obtained either from the Fmoc-deprotection of N-phthalimide 4a or from the reaction between 3-bromopropylamine and N-hydroxyphthalimide, both reactions involving an unusual rearrangement mechanism.Sulphonated derivatives 9, 16, upon Mitsunobu condensation with N-protected 3-aminopropanol or N-alkylation with N-(bromoalkyl)phthalimides, afforded the fully protected spermidine and spermine oxa-analogues.Subsequent sequential deprotection gave spermidine analogues 14.Using the same strategy, spermine oxa-analogues 19 was synthesised. - Keywords: polyamines; oxa-analogues of polyamines; polyamine homologues; rearrangement; synthesis