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157891-92-4

157891-92-4

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157891-92-4 Usage

Chemical Properties

Colourless or nearly colourless solid

Check Digit Verification of cas no

The CAS Registry Mumber 157891-92-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,5,7,8,9 and 1 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 157891-92:
(8*1)+(7*5)+(6*7)+(5*8)+(4*9)+(3*1)+(2*9)+(1*2)=184
184 % 10 = 4
So 157891-92-4 is a valid CAS Registry Number.

157891-92-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-O-TRITYL-6-O-DESMETHYL-DIPRENORPHINE

1.2 Other means of identification

Product number -
Other names TDPN

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:157891-92-4 SDS

157891-92-4Relevant articles and documents

Synthesis and evaluation of three structurally related 18F- labeled orvinols of different intrinsic activities: 6-O-[18F] fluoroethyl-diprenorphine ([18F]FDPN), 6-O-[18F] fluoroethyl-buprenorphine ([18F]FBPN), and 6-O-[18F] fluoroethyl-phenethyl-orvinol ([18F]FPEO)

Schoultz, Bent W.,Hj?rnevik, Trine,Reed, Brian J.,Marton, János,Coello, Christopher S.,Willoch, Frode,Henriksen, Gjermund

, p. 5464 - 5469 (2014/07/08)

We report the synthesis and biological evaluation of a triplet of 6-O- 18F-fluoroethylated derivatives of structurally related orvinols that span across the full range of intrinsic activities, the antagonist diprenorphine, the partial agonist buprenorphine, and the full agonist phenethyl-orvinol. [18F]fluoroethyl-diprenorphine, [ 18F]fluoroethyl-buprenorphine, and [18F]fluoroethyl- phenethyl-orvinol were prepared in high yields and quality from their 6-O-desmethyl-precursors. The results indicate suitable properties of the three 6-O-18F-fluoroethylated derivatives as functional analogues to the native carbon-11 labeled versions with similar pharmacological properties.

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