3-O-TRITYL-6-O-DESMETHYL-DIPRENORPHINE

Base Information

Chemical Name:3-O-TRITYL-6-O-DESMETHYL-DIPRENORPHINE
CAS No.:157891-92-4
Molecular Formula:C44H47 N O4
Molecular Weight:653.861
Hs Code.:
Mol file:157891-92-4.mol

Synonyms:TDPN;3-O-TRITYL-6-O-DESMETHYL-DIPRENORPHINE;6,14-ETHENOMORPHINAN-7-METHANOL, 17-(CYCLOPROPYLMETHYL)-4,5-EPOXY-18,19-DIHYDRO-6-HYDROXY-ALPHA,ALPHA-DIMETHYL-3-(TRIPHENYLMETHOXY)-, (5ALPHA, 7ALPHA);6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-4,5-epoxy-18,19-dihydro-6-hydroxy- a,a-dimethyl-3-(triphenylmethoxy)-, (5a, 7a)

Suppliers and Price of 3-O-TRITYL-6-O-DESMETHYL-DIPRENORPHINE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-O-TRITYL-6-O-DESMETHYL-DIPRENORPHINE 95.00%
5MG
$ 499.16

Total 2 raw suppliers

Chemical Property of 3-O-TRITYL-6-O-DESMETHYL-DIPRENORPHINE

Chemical Property:

PKA:14.11±0.40(Predicted)
Flash Point:166.8 °C
PSA：62.16000
Density:1.16 g/cm³
LogP:7.33670

Purity/Quality:

99% ^*data from raw suppliers

3-O-TRITYL-6-O-DESMETHYL-DIPRENORPHINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 3-O-TRITYL-6-O-DESMETHYL-DIPRENORPHINE

There total 1 articles about 3-O-TRITYL-6-O-DESMETHYL-DIPRENORPHINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 76-83-5
trityl chloride

: 113707-18-9
6-O-desmethyl-diprenorphine

: 157891-92-4
3-O-trityl-6-O-desmethyl-diprenorphine

Guidance literature:: With triethylamine; In dichloromethane;
DOI:10.1021/jm500503k

Reference yield: 65.0%

: 762-49-2
2-fluoroethyl bromide

: 157891-92-4
3-O-trityl-6-O-desmethyl-diprenorphine

: 1426174-15-3
(5R,6R,7R,9R,13S,14S)-(5α,7α)-17-cyclopropylmethyl4,5-epoxy-18,19-dihydro-6-(2-fluoroethoxy)-3-triphenylmethoxy-α,α-dimethyl-6,14-ethenomorphinan-7-methanol

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; mineral oil;
DOI:10.1021/jm500503k

Reference yield: 64.0%

: 762-51-6
1-fluoro-2-iodoethane

: 157891-92-4
3-O-trityl-6-O-desmethyl-diprenorphine

: 1426174-15-3
(5R,6R,7R,9R,13S,14S)-(5α,7α)-17-cyclopropylmethyl4,5-epoxy-18,19-dihydro-6-(2-fluoroethoxy)-3-triphenylmethoxy-α,α-dimethyl-6,14-ethenomorphinan-7-methanol

Guidance literature:: 3-O-trityl-6-O-desmethyl-diprenorphine; With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.25h; Inert atmosphere;

1-fluoro-2-iodoethane; In N,N-dimethyl-formamide; for 24h; Inert atmosphere;
DOI:10.2174/1570178617999200719153812