1579248-68-2Relevant academic research and scientific papers
Folate-vinca alkaloid conjugates for cancer therapy: A structure-activity relationship
Leamon, Christopher P.,Vlahov, Iontcho R.,Reddy, Joseph A.,Vetzel, Marilynn,Santhapuram, Hari Krishna R.,You, Fei,Bloomfield, Alicia,Dorton, Ryan,Nelson, Melissa,Kleindl, Paul,Vaughn, Jeremy F.,Westrick, Elaine
, p. 560 - 568 (2014/04/03)
Vintafolide is a potent folate-targeted vinca alkaloid small molecule drug conjugate (SMDC) that has shown promising results in multiple clinical oncology studies. Structurally, vintafolide consists of 4 essential modules: (1) folic acid, (2) a hydrophili
