1579278-75-3Relevant academic research and scientific papers
Regioselective hydration of terminal halo-substituted propargyl carboxylates by gold catalyst: Synthesis of α-acyloxy α'-halo ketones
Ghosh, Nayan,Nayak, Sanatan,Prabagar,Sahoo, Akhila K.
, p. 2453 - 2462 (2014/04/17)
Regioselective hydration of the terminal halo-substituted propargyl carboxylate by gold(I) catalyst is reported. The mild catalytic conditions tolerate common acid-labile protecting groups, and a wide variety of α-acyloxy α'-halo ketones are efficiently synthesized within a short reaction time. The α-acyloxy α'-halo ketones are used for the synthesis of 2-aminothiazoles.
