157928-46-6

Basic information

• Product Name: (β,β-difluoro-α-phenylvinyl)phenylsulfide
• Synonyms: (β,β-difluoro-α-phenylvinyl)phenylsulfide
• CAS NO: 157928-46-6
• Molecular Weight: 248.296
• Mol File: 157928-46-6.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (β,β-difluoro-α-phenylvinyl)phenylsulfide(CAS DataBase Reference)
• NIST Chemistry Reference: (β,β-difluoro-α-phenylvinyl)phenylsulfide(157928-46-6)
• EPA Substance Registry System: (β,β-difluoro-α-phenylvinyl)phenylsulfide(157928-46-6)

Safety Data

• Hazardous Substances Data: 157928-46-6(Hazardous Substances Data)

Upstream product

• 949-00-8 phenyl dithiobenzoate 
• 120801-75-4 trimethylsilyl-2,2-difluoro-2-(fluorosulphonyl)acetate 

Downstream Products

• 245544-03-0 (β,β-difluoro-α-phenylvinyl)phenylsulfone 

Relevant articles and documents

Synthesis of sulfanylated difluoroalkenes: Electrophilic difluoromethylidenation of dithioesters with difluorocarbene

Electrophilic difluoromethylidenation of dithioesters was achieved in high yields via the reaction with difluorocarbene. When aryl or alkyl dithiocarboxylates were treated with trimethylsilyl 2, 2-difluoro-2-fluorosulfonylacetate in the presence of 5 mol % of a Proton Sponge catalyst, the in situ generated difluorocarbene reacted with the dithioesters to afford 2-sulfanylated 1, 1-difluoro-1-alkenes via difluorothiiranes. This reaction can be considered as an electrophilic counterpart of the Wittig-type difluoromethylidenation of carbonyl compounds with nucleophilic difluoromethylene ylides.

EXOCYCLIZATION OF NOVEL β,β-DIFLUORO-α-PHENYLVINYL SULFIDE WITH BIDENTATE HETEROATOM(N,O,S) NUCLEOPHILES

The exocyclization of novel β,β-difluoro-α-phenylvinyl sulfide with bidentate heteroatom (N, O, S) nucleophiles afforded various types of heterocyclic ketene acetals (O,O-, O,S-, S,S-, N,N-, N,O-, N,S-).The ease of exocyclization depended on the ring size