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2-((4-(benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl dihydrogen phosphate is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

1579965-12-0

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1579965-12-0 Usage

Molecular structure

The compound consists of a quinazoline core with a benzo[d]thiazol-5-ylamino group and a tert-butylsulfonyl group attached to it, as well as an ethyl dihydrogen phosphate group.

Biological activity

The compound has potential biological activities and is commonly used in pharmaceutical research and drug development.

Potential applications

The compound may have application in the treatment of various diseases and disorders, but further study is needed to understand its full potential.

Unique chemical structure

The compound's unique structure makes it an interesting target for synthetic organic chemistry and medicinal chemistry research.

Check Digit Verification of cas no

The CAS Registry Mumber 1579965-12-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,7,9,9,6 and 5 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1579965-12:
(9*1)+(8*5)+(7*7)+(6*9)+(5*9)+(4*6)+(3*5)+(2*1)+(1*2)=240
240 % 10 = 0
So 1579965-12-0 is a valid CAS Registry Number.

1579965-12-0Downstream Products

1579965-12-0Relevant academic research and scientific papers

Discovery of a first-in-class receptor interacting protein 2 (RIP2) kinase specific clinical candidate, 2-((4-(Benzo[ d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl dihydrogen phosphate, for the treatment of inflammatory diseases

Haile, Pamela A.,Casillas, Linda N.,Votta, Bartholomew J.,Wang, Gren Z.,Charnley, Adam K.,Dong, Xiaoyang,Bury, Michael J.,Romano, Joseph J.,Mehlmann, John F.,King, Bryan W.,Erhard, Karl F.,Hanning, Charles R.,Lipshutz, David B.,Desai, Biva M.,Capriotti, Carol A.,Schaeffer, Michelle C.,Berger, Scott B.,Mahajan, Mukesh K.,Reilly, Michael A.,Nagilla, Rakesh,Rivera, Elizabeth J.,Sun, Helen H.,Kenna, John K.,Beal, Allison M.,Ouellette, Michael T.,Kelly, Mike,Stemp, Gillian,Convery, Maíre A.,Vossenk?mper, Anna,Macdonald, Thomas T.,Gough, Peter J.,Bertin, John,Marquis, Robert W.

, p. 6482 - 6494 (2019/08/20)

RIP2 kinase has been identified as a key signal transduction partner in the NOD2 pathway contributing to a variety of human pathologies, including immune-mediated inflammatory diseases. Small-molecule inhibitors of RIP2 kinase or its signaling partners on

PRODRUGS OF AMINO QUINAZOLINE KINASE INHIBITOR

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, (2014/04/03)

Disclosed are compounds having Formula (I); wherein X is as defined herein, and methods of making and using the same.

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