206190-25-2

Basic information

• Product Name: 6-iodo-7-Methoxyquinazolin-4(1H)-one
• Synonyms: 6-iodo-7-Methoxyquinazolin-4(1H)-one;6-Iodo-7-methoxy-4(1H)-quinazolinone;6-iodo-7-methoxyquinazolin-4-ol;6-Iodo-7-methoxy-1H-quinazolin-4-one;4(3H)-Quinazolinone, 6-iodo-7-methoxy-
• CAS NO: 206190-25-2
• Molecular Formula: C₉H₇IN₂O₂
• Molecular Weight: 302.06855
• Mol File: 206190-25-2.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Density: 2.00±0.1 g/cm3 (20 oC,760 mmHg), 计算值
• CAS DataBase Reference: 6-iodo-7-Methoxyquinazolin-4(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 6-iodo-7-Methoxyquinazolin-4(1H)-one(206190-25-2)
• EPA Substance Registry System: 6-iodo-7-Methoxyquinazolin-4(1H)-one(206190-25-2)

Safety Data

• Hazardous Substances Data: 206190-25-2(Hazardous Substances Data)

Usage

General Description

6-Iodo-7-Methoxyquinazolin-4(1H)-one is a chemical compound with the molecular formula C9H6IN2O2. It is a quinazolinone derivative with a molecular weight of 288.06 g/mol. 6-iodo-7-Methoxyquinazolin-4(1H)-one is a white to off-white solid that is sparingly soluble in water but soluble in organic solvents. 6-Iodo-7-Methoxyquinazolin-4(1H)-one has potential pharmaceutical applications, particularly in the development of new drugs for various therapeutic uses. It is used as a building block in organic synthesis and medicinal chemistry to create novel compounds with desired pharmacological properties. The unique structure of 6-Iodo-7-Methoxyquinazolin-4(1H)-one makes it a valuable intermediate in the synthesis of various biologically active molecules. Further research and development of this compound may lead to the discovery of new pharmaceutical agents for the treatment of diseases.

Upstream product

• 463-52-5 formamidine 
• 4294-95-5 4-methoxyanthranilic acid 
• 50413-30-4 methyl 2-amino-4-methoxybenzoate 
• 103096-05-5 2-amino-4-methoxy-benzoic acid ethyl ester 
• 7790-99-0 Iodine monochloride 

Downstream Products

• 1579965-12-0 2-((4-(benzo[d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl dihydrogen phosphate 

Relevant articles and documents

Discovery of a first-in-class receptor interacting protein 2 (RIP2) kinase specific clinical candidate, 2-((4-(Benzo[ d]thiazol-5-ylamino)-6-(tert-butylsulfonyl)quinazolin-7-yl)oxy)ethyl dihydrogen phosphate, for the treatment of inflammatory diseases

RIP2 kinase has been identified as a key signal transduction partner in the NOD2 pathway contributing to a variety of human pathologies, including immune-mediated inflammatory diseases. Small-molecule inhibitors of RIP2 kinase or its signaling partners on

PRODRUGS OF AMINO QUINAZOLINE KINASE INHIBITOR

Disclosed are compounds having Formula (I); wherein X is as defined herein, and methods of making and using the same.

4-aminoquinazolone derivatives

This invention relates to certain 4-aminoquinazoline derivatives of the formula and their pharmaceutically acceptable salts wherein R1, Q1, m, n, and Z are defined as in the specification. The compounds of formula I and pharmaceutically acceptable salts are useful for the treatment of hyperproliferative disorders and conditions in mammals.