1579996-69-2

Upstream product

• 1579996-67-0 (2R,3S,4S)-2,3-bis(benzyloxy)-5-(trityloxy)pentane-1,4-diol 
• 124-63-0 methanesulfonyl chloride 
• 1579996-66-9 (2R,3R,4S)-2,3-bis(benzyloxy)-5-(trityloxy)pentane-1,4-diyl diacetate 
• 1579996-60-3 (2R,3R,4R)-2,3-bis(benzyloxy)-5-(trityloxy)pentane-1,4-diyl dimethanesulfonate 
• 1579996-59-0 (2R,3S,4R)-2,3-bis(benzyloxy)-5-(trityloxy)pentane-1,4-diol 
• 1579996-58-9 (2R,3S,4S)-3,4-bis(benzyloxy)-5-oxo-1-(trityloxy)pentan-2-yl formate 

Downstream Products

• 113626-57-6 (2R,3S,4R)-N-benzyl-3,4-bis(benzyloxy)-2-hydroxymethylpyrrolidine 
• 1579996-79-4 tert-butyl (2R,3S,4R)-3,4-bis(benzyloxy)-2-(hydroxymethyl)-pyrrolidine-1-carboxylate 
• 1579996-80-7 tert-butyl (2R,3S,4R)-3,4-bis(benzyloxy)-2-((R)-1-hydroxyallyl)-pyrrolidine-1-carboxylate 
• 1579996-93-2 (2R,3S,4R)-1-allyl-3,4-bis(benzyloxy)-2-((R)-1-(benzyloxy)allyl)-pyrrolidine 
• 1579996-95-4 (1S,2R,8R,8aR)-1,2,8-tris(benzyloxy)-1,2,3,5,8,8a-hexahydroindolizine 
• 72741-87-8 swainsonine 
• 117719-25-2 C₁₉H₂₃NO₃ 
• 1579996-70-5 (2R,3S,4R)-1-benzyl-3,4-bis(benzyloxy)-2-(trityloxymethyl)-pyrrolidine 

Relevant academic research and scientific papers

Synthesis of pyrrolidine iminosugars, (-)-lentiginosine, (-)-swainsonine and their 8a-epimers from d-glycals

Synthesis of pyrrolidine iminosugars has been described from d-glycals via dihydroxylation, oxidative cleavage and double nucleophilic displacement as the key steps. The pyrrolidines obtained have been utilized for the synthesis of important bicyclic iminosugars, viz. (-)-lentiginosine and (-)-swainsonine and their 8a-epimers, which are known to be glycosidase inhibitors.