1579997-01-5

Upstream product

• 1579996-72-7 C₁₉H₂₃NO₃ 
• 1579996-73-8 C₂₄H₂₉NO₅ 
• 1579996-75-0 tert-butyl (2S,3S,4R)-3,4-bis(benzyloxy)-2-((R)-1-hydroxyallyl)-pyrrolidine-1-carboxylate 
• 1579996-71-6 tert-butyl (2S,3S,4R)-3,4-bis(benzyloxy)-2-(hydroxymethyl)-pyrrolidine-1-carboxylate 
• 1579996-64-7 ((2S,3S,4R)-1-benzyl-3,4-bis(benzyloxy)pyrrolidin-2-yl)methanol 
• 1579996-62-5 (2S,3S,4R)-1-benzyl-3,4-bis(benzyloxy)-2-(trityloxymethyl)-pyrrolidine 
• 1579996-60-3 (2R,3R,4R)-2,3-bis(benzyloxy)-5-(trityloxy)pentane-1,4-diyl dimethanesulfonate 
• 1579996-59-0 (2R,3S,4R)-2,3-bis(benzyloxy)-5-(trityloxy)pentane-1,4-diol 
• 1579996-58-9 (2R,3S,4S)-3,4-bis(benzyloxy)-5-oxo-1-(trityloxy)pentan-2-yl formate 

Relevant academic research and scientific papers

Synthesis of pyrrolidine iminosugars, (-)-lentiginosine, (-)-swainsonine and their 8a-epimers from d-glycals

Synthesis of pyrrolidine iminosugars has been described from d-glycals via dihydroxylation, oxidative cleavage and double nucleophilic displacement as the key steps. The pyrrolidines obtained have been utilized for the synthesis of important bicyclic iminosugars, viz. (-)-lentiginosine and (-)-swainsonine and their 8a-epimers, which are known to be glycosidase inhibitors.