158001-04-8

Basic information

• Product Name: IMidazo[1,2-a]pyridine-6-carboxylic acid, ethyl ester
• Synonyms: IMidazo[1,2-a]pyridine-6-carboxylic acid, ethyl ester
• CAS NO: 158001-04-8
• Molecular Formula: C₁₀H₁₀N₂O₂
• Molecular Weight: 190.1986
• Mol File: 158001-04-8.mol

Chemical Properties

• Appearance: /
• Density: 1.22±0.1 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 5.18±0.50(Predicted)
• CAS DataBase Reference: IMidazo[1,2-a]pyridine-6-carboxylic acid, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: IMidazo[1,2-a]pyridine-6-carboxylic acid, ethyl ester(158001-04-8)
• EPA Substance Registry System: IMidazo[1,2-a]pyridine-6-carboxylic acid, ethyl ester(158001-04-8)

Safety Data

• Hazardous Substances Data: 158001-04-8(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
IMidazo[1,2-a]pyridine-6-carboxylic acid, ethyl ester is used as a synthetic intermediate for the preparation of various organic compounds. Its unique structure allows for the creation of a wide range of molecules with potential applications in different fields.
Used in Research Settings:
In the field of chemistry, IMidazo[1,2-a]pyridine-6-carboxylic acid, ethyl ester is used as a research compound to study its properties and potential applications. Its complex structure and reactivity make it an interesting subject for scientific investigation.
Used in Pharmaceutical Industry:
Although not commonly discussed, IMidazo[1,2-a]pyridine-6-carboxylic acid, ethyl ester may have potential applications in the pharmaceutical industry as a precursor for the development of new drugs. Its unique chemical structure could be utilized in the synthesis of novel therapeutic agents.

Upstream product

• 107-20-0 2-chloroethanal 
• 39658-41-8 ethyl-6-amino-nicotinate 

Downstream Products

• 132213-07-1 6-(hydroxymethyl)imidazo[1,2-a]pyridine 
• 116355-16-9 6-imidazo<1,2-a>pyridinecarboxaldehyde 
• 139022-25-6 imidazo[1,2-a]pyridine-6-carboxylic acid 
• 372147-65-4 (Z)-ethyl α-[(triphenylphosphoranylidene)amino]-β-(imidazo[1,2-a]pyridin-6-yl)propenoate 

Relevant articles and documents

P2X3 AND/OR P2X2/3 COMPOUNDS AND METHODS

The present disclosure provides novel compounds and methods for preparing and using these compounds. In one embodiment, the compounds are of the structure of formula (I), wherein R1-R7 are defined herein. In a further embodiment, these compounds are useful in method for regulating one or both of the P2X3 or P2X2/3 receptors. In another embodiment, these compounds are useful for treating pain in patients by administering one or more of the compounds to a patient. In another embodiment, these compounds are useful for treating respiratory dysfunction in patients by administering one or more of the compounds to a patient.

Heterocyclization of functionalized vinylic derivatives of imidazo[1,2-α]pyridines

Heterocyclization of functionalized vinylic derivatives of imidazo[1,2-α]pyridines was explored experimentally and theoretically using semiempirical AM1 and ab initio methods. A range of functionalized vinylic derivatives (azido, amino, and carbodiimide groups) were prepared for conversion into pyrroloazaindoles 19-22, imidazo[1,x]-; (x=5, 6, 7, 8), [2,6]-, and [2,7]naphthyridines 28-30, 35-38 by thermal reaction. In the case of vinylic groups in the 5 position, peri annulation also was observed. The experimental and theoretical data are compared and discussed.

6-heterocyclyl pyrazolo [3,4-d]pyrimidin-4-ones and compositions and method of use thereof

Novel 6-heterocyclyl-pyrazolo[3,4-d]pyrimidin-4-ones, useful in treating cardiovascular disease, are prepared by reacting a 5-amino-1H-pyrazole-4-carboxamide with heterocyclylcarboxaldehyde or by reacting a 5-amino-1H-pyrazole-4-carbonitrile with a heterocyclylcarboxamidine, followed by diazotization and hydrolysis of the resulting 4-amino-6-heterocyclyl-pyrazolo[3,4-d]pyrimidine.