1580443-52-2Relevant articles and documents
Benzofuran derivatives as a novel class of inhibitors of mTOR signaling
Salomé, Christophe,Narbonne, Vanessa,Ribeiro, Nigel,Thuaud, Frédéric,Serova, Maria,De Gramont, Armand,Faivre, Sandrine,Raymond, Eric,Désaubry, Laurent
, p. 41 - 49 (2014/02/14)
High-throughput screening (HTS) hit 1 was previously identified as an inhibitor of the Akt/mTOR (Akt/mammalian target of rapamycin) signaling, which is a major target in oncology. The cytotoxicity of 1 was determined on a panel of human cancer cells lines
