1580445-37-9Relevant academic research and scientific papers
Discovery of a cyclopentylamine as an orally active dual NK1 receptor antagonist-serotonin reuptake transporter inhibitor
Wu, Yong-Jin,He, Huan,Gao, Qi,Wu, Dedong,Bertekap, Robert,Westphal, Ryan S.,Lelas, Snjezana,Newton, Amy,Wallace, Tanya,Taber, Matthew,Davis, Carl,Macor, John E.,Bronson, Joanne
, p. 1611 - 1614 (2014)
Cyclopentylamine 4 was identified as a potent dual NK1R antagonist-SERT inhibitor. This compound demonstrated significant oral activity in the gerbil forced swimming test, suggesting that dual NK1R antagonists-SERT inhibitors may be
