1580462-16-3Relevant academic research and scientific papers
Low melting oxalic acid/proline mixture as dual solvent/catalyst for efficient synthesis of 13-aryl-13H-benzo[g]benzothiazolo[2,3-b]buinazoline-5,4-diones under microwave irradiation
Ma, Cui-Ting,Liu, Peng,Wu, Wei,Zhang, Zhan-Hui
, p. 606 - 611 (2017)
Oxalic acid and proline based deep eutectic solvent (DES) has been identified as an effective catalyst and environmentally benign reaction medium for one-pot synthesis of 13-aryl-13H-benzo[g]benzothiazolo[2,3-b]quinazoline-5,14-diones via three-component
Synthesis and antiproliferative evaluation of 13-aryl-13H-benzo[g] benzothiazolo [2,3-b]quinazoline-5,14-diones
Wu, Liqiang,Zhang, Chong,Li, Weilin
supporting information, p. 1462 - 1465 (2014/03/21)
A simple synthesis of novel 13-aryl-13H-benzo[g]benzothiazolo [2,3-b]quinazoline-5,14-dione derivatives was accomplished in excellent yields via the reaction of 2-aminobenzothiazole, aromatic aldehydes and 2-hydroxy-1,4-naphthoquinone in the presence of amberlyst-15. The antiproliferative activities of all the synthesized compounds were assessed on two different human cancer cell lines (HepG2 and Hela), and the results showed that most of the new compounds showed good to potent cytotoxic activities.
