158053-41-9Relevant academic research and scientific papers
RA-III lactone, a 19-membered ring analogue of RAs, antitumor cyclic hexapeptide
Hitotsuyanagi, Yukio,Kondo, Kazuyuki,Takeya, Koichi,Itokawa, Hideji
, p. 2191 - 2194 (1994)
Antitumor cyclic hexapeptide RA-III (2) has been converted to a lactone analogue 3 which is the first analogue of RAs in which the 18-membered macro ring was modified. 3 was found to possess promising antitumor activity, and its solution conformation was established by NMR spectroscopy.
