158090-56-3Relevant academic research and scientific papers
Synthesis and activities of oxidative metabolites of the anti-arthritic drug candidate S-2474
Inagaki, Masanao,Jyoyama, Hirokuni,Ono, Takashi,Yamada, Katsutoshi,Kobayashi, Mika,Baba, Takahiko,Touchi, Akira,Iwatani, Kouji,Ohkawa, Tomoyuki,Matsumoto, Saichi,Tsuri, Tatsuo
, p. 2415 - 2419 (2007/10/03)
We have synthesized and characterized some oxidative metabolites of S-2474. In this study, we discovered a novel skeleton, the 2,3-dihydrobenzofuran derivative, which inhibited PGE2 production at a very low concentration and was effective in th
