158090-53-0Relevant academic research and scientific papers
Synthesis and activities of oxidative metabolites of the anti-arthritic drug candidate S-2474
Inagaki, Masanao,Jyoyama, Hirokuni,Ono, Takashi,Yamada, Katsutoshi,Kobayashi, Mika,Baba, Takahiko,Touchi, Akira,Iwatani, Kouji,Ohkawa, Tomoyuki,Matsumoto, Saichi,Tsuri, Tatsuo
, p. 2415 - 2419 (2007/10/03)
We have synthesized and characterized some oxidative metabolites of S-2474. In this study, we discovered a novel skeleton, the 2,3-dihydrobenzofuran derivative, which inhibited PGE2 production at a very low concentration and was effective in th
Benzylidene derivatives
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, (2008/06/13)
Benzylidene derivatives having anti-inflammatory activities, are shown by the following formula I: STR1 wherein A is -CH2 - or -CH2 CH2 -; B is a bond or -CH2 -, -CHOH-, -CO-, -O-, or A and B may taken together
