1581720-58-2Relevant academic research and scientific papers
An isothiourea-catalyzed asymmetric [2,3]-rearrangement of allylic ammonium ylides
West, Thomas H.,Daniels, David S. B.,Slawin, Alexandra M. Z.,Smith, Andrew D.
supporting information, p. 4476 - 4479 (2014/04/17)
Benzotetramisole promotes the catalytic asymmetric [2,3]-rearrangement of allylic quaternary ammonium salts (either isolated or prepared in situ from p-nitrophenyl bromoacetate and the corresponding allylic amine), generating syn-α-amino acid derivatives with excellent diastereo- and enantioselectivity (up to >95:5 dr; up to >99% ee).
