158252-23-4

Basic information

• Product Name: 3-Cyclohexene-1-carboxylicacid,2-methoxy-,(1S-cis)-(9CI)
• Synonyms: 3-Cyclohexene-1-carboxylicacid,2-methoxy-,(1S-cis)-(9CI)
• CAS NO: 158252-23-4
• Molecular Formula: C₈H₁₂O₃
• Molecular Weight: 156.18
• Product Categories: CARBOXYLICACID
• Mol File: 158252-23-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-Cyclohexene-1-carboxylicacid,2-methoxy-,(1S-cis)-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Cyclohexene-1-carboxylicacid,2-methoxy-,(1S-cis)-(9CI)(158252-23-4)
• EPA Substance Registry System: 3-Cyclohexene-1-carboxylicacid,2-methoxy-,(1S-cis)-(9CI)(158252-23-4)

Safety Data

• Hazardous Substances Data: 158252-23-4(Hazardous Substances Data)

Upstream product

• 127943-89-9 2-hydroxy-3-cyclohexenyl-1-carboxylic acid 
• 77-78-1 dimethyl sulfate 
• 158195-43-8 acetic acid (6S)-(10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]decane-4-carbonyl)-(1R)-cyclohex-2-enyl ester 
• 159517-29-0 (1S,2R)-2-hydroxy-3-cyclohexanecarboxylic acid 

Downstream Products

• 159415-28-8 2-methoxy-3-cyclohexenyl-1-carboxylic acid fluoride 
• 159581-79-0 methyl (1S,2S)-2-methoxy-3-oxo-1-cyclohexane carboxylate 
• 158195-46-1 methyl (1S,2S,3R)-3-hydroxy-2-methoxy-1-cyclohexanecarboxylate 
• 159581-81-4 methyl (1S,2S)-3-(N-hydroxylamino)-2-methoxycyclohexane carboxylate 
• 174709-87-6 (1S,2S,3R)-3-hydroxy-2-methoxycyclohexanecarboxylic acid 
• 174709-89-8 (1S,2S)-2-methoxy-3-oxocyclohexanecarbonyl fluoride 
• 174709-88-7 (1S,2S)-2-methoxy-3-oxocyclohexanecarboxylic acid 
• 174709-90-1 (1S,2S,3R)-4-<(tert-butyldimethylsilyl)oxy>-1-isopropyl-2-(methoxymethoxy)-3-methylbutyl (1S,2S)-2-methoxy-3-oxocyclohexanecarboxylate 

Relevant articles and documents

Esterification via acid fluoride activation

The esterification of sterically hindered or non-nucleophilic alcohols may often be problematic. The reaction of alcohols with acid fluorides is reported to be superior to standard acid activation protocols frequently used for difficult esterifications. T

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An asymmetric Diels-Alder reaction in the presence of 3.0 M lithium perchlorate-diethyl ether was used to generate the initial stereochemistry for a cyclohexane amino acid (3), a key intermediate in the preparation of a fused ring didemnin analog. This constrained ring macrocycle should provide insight into the binding site conformation of the bioactive species.