174709-89-8

Basic information

• Product Name: Cyclohexanecarbonyl fluoride, 2-methoxy-3-oxo-, (1S-cis)- (9CI)
• Synonyms: Cyclohexanecarbonyl fluoride, 2-methoxy-3-oxo-, (1S-cis)- (9CI)
• CAS NO: 174709-89-8
• Molecular Formula: C₈H₁₁FO₃
• Molecular Weight: 174.1695432
• Product Categories: ACIDHALIDE
• Mol File: 174709-89-8.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Cyclohexanecarbonyl fluoride, 2-methoxy-3-oxo-, (1S-cis)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Cyclohexanecarbonyl fluoride, 2-methoxy-3-oxo-, (1S-cis)- (9CI)(174709-89-8)
• EPA Substance Registry System: Cyclohexanecarbonyl fluoride, 2-methoxy-3-oxo-, (1S-cis)- (9CI)(174709-89-8)

Safety Data

• Hazardous Substances Data: 174709-89-8(Hazardous Substances Data)

Upstream product

• 174709-87-6 (1S,2S,3R)-3-hydroxy-2-methoxycyclohexanecarboxylic acid 
• 159517-29-0 (1S,2R)-2-hydroxy-3-cyclohexanecarboxylic acid 
• 174709-88-7 (1S,2S)-2-methoxy-3-oxocyclohexanecarboxylic acid 
• 158195-43-8 acetic acid (6S)-(10,10-dimethyl-3,3-dioxo-3λ⁶-thia-4-aza-tricyclo[5.2.1.0^1,5]decane-4-carbonyl)-(1R)-cyclohex-2-enyl ester 
• 158195-44-9 (1S,4S,5S,8S)-4-Iodo-8-methoxy-6-oxa-bicyclo[3.2.1]octan-7-one 
• 158252-23-4 (1S,2R)-2-methoxy-3-cyclohexenyl-1-carboxylic acid 
• 158195-45-0 (1S,5R,8S)-8-Methoxy-6-oxa-bicyclo[3.2.1]octan-7-one 

Downstream Products

• 174709-90-1 (1S,2S,3R)-4-<(tert-butyldimethylsilyl)oxy>-1-isopropyl-2-(methoxymethoxy)-3-methylbutyl (1S,2S)-2-methoxy-3-oxocyclohexanecarboxylate 

Relevant articles and documents

Synthetic routes to a constrained ring analog of didemnin B

The didemnin class of biologically active cyclodepsipeptides, isolated from a marine tunicate, has shown antitumor, antiviral, and immunosuppressive activities. Synthetic studies were undertaken to prepare a modified analog of one of the most potent congeners, didemnin B (1). The side chain of the isostatine unit was tethered into the macrocycle via a cyclohexane ring in order to provide a more rigid conformation and determine the importance of this unit in bioactive compounds. This modification created a new macrocycle core and generated a diastereomeric mixture of a constrained analog of didemnin B (2).