158265-22-6

Upstream product

• 158265-19-1 2-(2-chloroquinolin-4-yl)acetic acid methyl ester 
• 21298-80-6 2-(2-oxo-1,2-dihydroquinoline-4-yl)acetic acid 
• 103702-23-4 (2-oxo-1,2-dihydroquinolin-4-yl)acetic acid methylester 
• 158265-10-2 1-acetyl-4-dicyanomethylene-2-methoxy-1,4-dihydroquinoline 

Relevant academic research and scientific papers

A convenient synthesis of 4-β-(2-heterocycloalkyl)quinoline-4-ethanols as potential antimalarial agents

A convenient synthetic strategy to 4β-(2-heterocycloalkyl)quinoline-4-ethanols (3) has been developed which involves condensation of quinoline-4-acetic acid methyl seter (17) with lactam acetals 4 and 5 and lactim ether 6 followed by hydride reduction of the condensation products 18.