158271-97-7

Upstream product

• 106-94-5 propyl bromide 
• 158271-95-5 1-(2-hydroxy-1-phenylethyl)-1,5-dihydropyrrol-2-one 
• 25779-13-9 (S)-1-phenyl-1,2-ethanediol 

Relevant academic research and scientific papers

Diastereoselective bis-alkylation of chiral non-racemic α,β-unsaturated γ-lactams

A new chiral non-racemic γ-lactam 1 easily prepared in one step from (R)-(-)-phenylglycinol was bis-alkylated α to the carbonyl function in very high to complete diastereoselectivity. The stereochemistry at the so-formed chiral quaternary center was ascertained through an X-ray crystallographic study.