1582776-44-0

Basic information

• Product Name: C₃₂H₂₄FNO₃
• Synonyms: C₃₂H₂₄FNO₃
• CAS NO: 1582776-44-0
• Molecular Weight: 489.546
• Mol File: 1582776-44-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₂H₂₄FNO₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₂H₂₄FNO₃(1582776-44-0)
• EPA Substance Registry System: C₃₂H₂₄FNO₃(1582776-44-0)

Safety Data

• Hazardous Substances Data: 1582776-44-0(Hazardous Substances Data)

Upstream product

• 1582776-32-6 5,8-diphenyl-2-naphthoic acid 
• 1582776-31-5 methyl 5,8-diphenyl-2-naphthoate 
• 1027513-43-4 ethyl 3-fluoro-4-iodobenzoate 
• 1582776-34-8 5,8-diphenyl-2-naphthamide 
• 99970-75-9 methyl 5,8-diiodo-2-naphthoate 
• 2459-25-8 methyl naphthalene-2-carboxylate 

Downstream Products

• 1582776-50-8 C₃₀H₂₀FNO₃ 

Relevant articles and documents

Dual RXR agonists and RAR antagonists based on the stilbene retinoid scaffold

Arotinoids containing a C5,C8-diphenylnaphthalene-2-yl ring linked to a (C3-halogenated) benzoic acid via an ethenyl connector (but not the corresponding naphthamides), which are prepared by Horner-Wadsworth-Emmons reaction of naphthaldehydes and benzylphosphonates, display the rather unusual property of being RXR agonists (15-fold induction of the RXR reporter cell line was achieved at 3- to 10-fold lower concentration than 9-cis-retinoic acid) and RAR antagonists as shown by transient transactivation studies. The binding of such bulky ligands suggests that the RXR ligand-binding domain is endowed with some degree of structural elasticity.