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1583284-89-2

3-(6-(methylthio)-1-(prop-2-ynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)phenol is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 1583284-89-2 Structure

  • Basic information

    1. Product Name: 3-(6-(methylthio)-1-(prop-2-ynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)phenol
    2. Synonyms: 3-(6-(methylthio)-1-(prop-2-ynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)phenol
    3. CAS NO:1583284-89-2
    4. Molecular Formula:
    5. Molecular Weight: 311.367
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1583284-89-2.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 3-(6-(methylthio)-1-(prop-2-ynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)phenol(CAS DataBase Reference)
    10. NIST Chemistry Reference: 3-(6-(methylthio)-1-(prop-2-ynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)phenol(1583284-89-2)
    11. EPA Substance Registry System: 3-(6-(methylthio)-1-(prop-2-ynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ylamino)phenol(1583284-89-2)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1583284-89-2(Hazardous Substances Data)

1583284-89-2 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1583284-89-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,5,8,3,2,8 and 4 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1583284-89:
(9*1)+(8*5)+(7*8)+(6*3)+(5*2)+(4*8)+(3*4)+(2*8)+(1*9)=202
202 % 10 = 2
So 1583284-89-2 is a valid CAS Registry Number.

1583284-89-2Relevant articles and documents

Exploring the chemical space around the privileged pyrazolo[3,4-d] pyrimidine scaffold: Toward novel allosteric inhibitors of T315I-mutated Abl

Vignaroli, Giulia,Mencarelli, Martina,Sementa, Deborah,Crespan, Emmanuele,Kissova, Miroslava,Maga, Giovanni,Schenone, Silvia,Radi, Marco,Botta, Maurizio

, p. 168 - 175 (2014/05/06)

A library of pyrazolo[3,4-d]pyrimidines, endowed with a high level of molecular diversity, has been developed applying a synthetic sequence that allowed C3, N1, C4, and C6 substitution. The enzymatic screening of this "privileged scaffold"-based compound collection, validated the use of a diversity-oriented approach in a field characteristically explored by target-oriented synthesis. In fact, several compounds showed high activity against the selected kinases (i.e., Src, Abl wt, and T315I mutated-form), furthermore and interestingly a new compound has emerged as an allosteric inhibitor of the T315I mutated-form of Abl, opening up new opportunities for the development of a novel class of noncompetitive inhibitors of Abl (T315I).

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