15835-74-2

Basic information

• Product Name: Acerosin
• Synonyms: Acerosin;5,7-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,8-dimethoxy-4H-1-benzopyran-4-one
• CAS NO: 15835-74-2
• Molecular Formula: C₁₈H₁₆O₈
• Molecular Weight: 360.3148
• Mol File: 15835-74-2.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 668.8°Cat760mmHg
• Flash Point: 246.3°C
• Appearance: /
• Density: 1.461g/cm³
• Vapor Pressure: 1.68E-18mmHg at 25°C
• Refractive Index: 1.649
• CAS DataBase Reference: Acerosin(CAS DataBase Reference)
• NIST Chemistry Reference: Acerosin(15835-74-2)
• EPA Substance Registry System: Acerosin(15835-74-2)

Safety Data

• Hazardous Substances Data: 15835-74-2(Hazardous Substances Data)

Usage

Definition

ChEBI: A trihydroxyflavone that is 5,7,3'-trihydroxyflavone with methoxy substituents at positions 6, 8 and 4' respectively.

InChI:InChI=1/C18H16O8/c1-23-11-5-4-8(6-9(11)19)12-7-10(20)13-14(21)17(24-2)15(22)18(25-3)16(13)26-12/h4-7,19,21-22H,1-3H3

Upstream product

• 520-33-2 (S)-2,3-dihydro-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-4-benzopyrone 
• 64726-90-5 (2S)-7-[[6-O-(6-deoxy-α-L-mannopyranosyl)-β-D-glucopyranosyl]oxy]-5-hydroxy-2-(3-hydroxy-4-methoxyphenyl)-2,3-dihydro-4H-1-benzopyran-4-one 
• 124-41-4 sodium methylate 

Relevant articles and documents

Semisynthesis of polymethoxyflavonoids from naringin and hesperidin

Polymethoxyflavonoids (PMFs) possess important biological activities, notably as anticancer agents. Semisynthesis of a series of PMFs were performed by glycoside hydrolysis, dehydrogenation, bromination, aromatic nucleophilic substitution, O-methylation, dimethyldioxirane oxidation and regioselective demethylation, starting from abundant and inexpensive natural sources naringin and hesperidin. A new synthetic method for selective methylation using CuBr catalysed and microwave-assisted reaction was developed, and the dimethyl dioxirane oxidation of flavones to flavonols was much improved. The new semisynthetic route has the advantages of easy availability of starting materials, simple operation and good yields.