158359-00-3Relevant academic research and scientific papers
Selective incorporation of CF2-group into the natural compounds molecules. Synthesis of 14,14-difluorocoriolic acid
Kornilov,Kulik,Sorochinsky,Kukhar
, p. 199 - 206 (2007/10/02)
The difluorides obtained in the reaction of DAST with appropriate ketones could serve as suitable starting materials for the selective incorporation of CF2-group into the molecules of the unsaturated chiral natural compounds. As an example, ste
Stereoselective synthesis of 14,14-difluorocoriolic acid
Kornilov, Andrew M.,Sorochinsky, Alexander E.,Kukhar, Valery P.
, p. 1015 - 1018 (2007/10/02)
An efficient, stereoselective synthesis of (R)-14,14-difluoro-13-hydroxy-9(Z),11(E)-octadecadienoic acid ((R)-14,14-difluorocoriolic acid) 2 starting from D-glyceraldehyde acetonide via the key intermediate (R)-3,3-difluoro-1,2-dihydroxyheptane 9 is repor
