15837-61-3Relevant academic research and scientific papers
Synthesis of new biheterocycles by a one-pot sonogashira coupling reaction
Deodhar, Mandar,Black, David Stc.,Kumar, Naresh
experimental part, p. 1489 - 1501 (2011/05/14)
Halogenated flavones, isoflavones and indoles were subjected to a one-pot Sonogashira coupling reaction to generate a series of new biheterocyclic compounds. The methodology can be readily adapted to the synthesis of a wide variety of substituted biheterocycles. The Japan Institute of Heterocyclic Chemistry.
Synthesis of gem-difluoromethylenated biflavonoid via the Suzuki coupling reaction
Zheng, Xing,Meng, Wei-Dong,Qing, Feng-Ling
, p. 8083 - 8085 (2007/10/03)
gem-Difluoromethylenated biflavonoid 1 was synthesized via the Suzuki coupling reaction. The key intermediate 6-iodonated flavone 4 was regioselectively synthesized by the use of AgOAc/I2 under mild conditions without handling of a strongly toxic reagent. The key step was the formation of a flavone 3′-boronate 3 using a palladium-catalyzed exchange of the corresponding 3′-iodonated flavone with a diboron reagent.
