1584705-70-3Relevant academic research and scientific papers
Cp?CoIII-catalyzed directed C-H trifluoromethylthiolation of 2-phenylpyridines and 6-arylpurines
Yoshida, Misaki,Kawai, Kentaro,Tanaka, Ryo,Yoshino, Tatsuhiko,Matsunaga, Shigeki
supporting information, p. 5974 - 5977 (2017/07/10)
Cp?CoIII-catalyzed directed C-H trifluoromethylthiolation using N-trifluoromethylthiodibenzenesulfonimide as an electrophilic SCF3 source is described. 6-Arylpurines, an important structural motif in medicinal chemistry, and 2-phenylpyridines selectively afforded mono-trifluoromethylthiolated products in moderate to good yields using an inexpensive first-row transition metal catalyst.
Palladium-catalyzed trifluoromethylthiolation of aryl C-H bonds
Xu, Chunfa,Shen, Qilong
supporting information, p. 2046 - 2049 (2014/05/06)
A method for monotrifluoromethylthiolation of arenes via palladium-catalyzed directed C-H bond activation was described. The reaction was compatible with a variety of functional groups. Initial mechanistic studies disclosed that the turnover limiting step of the catalytic cycle did not involve C-H activation.
