1584709-69-2

Upstream product

• 111462-38-5 1-O-benzyl-3,4-O-isopropylidene-D-erythritol ⁽¹²⁾ and 2-O-benzyl-3,4-O-isopropylidene-D-erythritol 

Downstream Products

• 1584709-62-5 (S)-3-(benzyloxy)-1-(4-chlorophenyl)-3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)propan-1-one 
• 1584709-63-6 (S)-3-(benzyloxy)-3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-1-(p-tolyl)propan-1-one 
• 1584709-64-7 (S)-3-(benzyloxy)-3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-1-phenylpropan-1-one 
• 1584709-65-8 (S)-3-(benzyloxy)-1-(3,4-dichlorophenyl)-3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)propan-1-one 
• 1584709-66-9 (S)-3-(benzyloxy)-3-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-1-(4-fluorophenyl)propan-1-one 
• 1584709-92-1 C₂₆H₃₁FN₂O₄ 

Relevant academic research and scientific papers

A defunctionalization concept for the convenient synthesis of bis(5-arylfuran-2-yl)methane scaffolds

The bis(5-arylfuran-2-yl)methane framework has been obtained through defunctionalization of aryl ketones, derived from abundantly available L-(+)-tartaric acid, under the influence of acid. The stereocomponents present in these starting aryl ketones have been found to be insignificant for this transformation. Formation of bis(5-arylfuran-2-yl)methane scaffold 1 has been achieved by using a defunctionalization concept involving aryl ketones 2 under the influence of acid. Ketones 2 are easily accessible from L-(+)-tartaric acid through an umpolung strategy using α-amino nitriles as acyl anion equivalents. The stereocomponent (threo/erythro) present in 2 was not significant for this transformation. Copyright