1584709-72-7

Upstream product

• 155301-38-5 (S)-4-[(R)-1-(benzyloxy)-2-bromoethyl]-2,2-dimethyl-1,3-dioxolane 
• 84379-53-3 2-O-benzyl-3,4-O-isopropylidene-L-threitol 
• 1584709-81-8 C₂₆H₃₁ClN₂O₄ 

Downstream Products

• 62645-46-9 Bis-<5-(4-Chlorphenyl)-2-furyl>-methan 
• 33342-29-9 5-(4-chlorophenyl)-2-hydroxymethylfuran 

Relevant academic research and scientific papers

A defunctionalization concept for the convenient synthesis of bis(5-arylfuran-2-yl)methane scaffolds

The bis(5-arylfuran-2-yl)methane framework has been obtained through defunctionalization of aryl ketones, derived from abundantly available L-(+)-tartaric acid, under the influence of acid. The stereocomponents present in these starting aryl ketones have been found to be insignificant for this transformation. Formation of bis(5-arylfuran-2-yl)methane scaffold 1 has been achieved by using a defunctionalization concept involving aryl ketones 2 under the influence of acid. Ketones 2 are easily accessible from L-(+)-tartaric acid through an umpolung strategy using α-amino nitriles as acyl anion equivalents. The stereocomponent (threo/erythro) present in 2 was not significant for this transformation. Copyright